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Found 2 of ic50 for drug = Dorzolamide Hydrochloride And Timolol Maleate
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Naia Metabolic

US Patent
LigandPNGBDBM50043906(CHEMBL269001 | Dorzolamide | MK-507 | US10172837, ...)
Affinity DataIC50:  9nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target6-phosphogluconate dehydrogenase, decarboxylating(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM50043906(CHEMBL269001 | Dorzolamide | MK-507 | US10172837, ...)
Affinity DataKi:  3.14E+6nM IC50:  1.41E+6nMAssay Description:The enzyme activities in the absence of drugs or chemicals were taken as 100%. For each drug or chemical, an activity%-(drug) graph was drawn and dr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed