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Found 11 of ic50 for drug = Eryzole
TargetRNA demethylase ALKBH5(Homo sapiens)TBA
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of recombinant human ALKBH5 catalytic AlkB domain (74 to 294 residues) transfected in Escherichia coli BL21 (DE3) using 8-mer m6A-ssDNA as...More data for this Ligand-Target Pair
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TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50:  8.53E+4nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
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TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50:  3.70E+5nMAssay Description:Inhibition of FTO (unknown origin)More data for this Ligand-Target Pair
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TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50:  5.10E+5nMAssay Description:Inhibition of human PHD2 expressed in H5 insect cellsMore data for this Ligand-Target Pair
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TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))TBA
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50:  5.70E+5nMAssay Description:Inhibition of human PHD3 expressed in H5 insect cellsMore data for this Ligand-Target Pair
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TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50:  7.10E+5nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
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TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))TBA
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50:  8.30E+5nMAssay Description:Inhibition of human PHD1 expressed in H5 insect cellsMore data for this Ligand-Target Pair
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TargetProlyl 4-hydroxylase(Paramecium bursaria Chlorella virus 1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
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TargetLysine-specific demethylase 5B(Homo sapiens (Human))TBA
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50:  1.40E+6nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
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TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Homo sapiens (Human))TBA
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of human FIH expressed in H5 insect cellsMore data for this Ligand-Target Pair