Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ic50 for drug = Focalin
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  19.9nMAssay Description:Inhibition of [3H]dopamine uptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  51nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK293 cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  83nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter using rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  122nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  224nMAssay Description:Inhibitory activity against [3H]dopamine uptake in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  788nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of [3H]-WIN- 35,428 Binding to theDopamine Transporter in Rhesus (Macaca mulatta) orCynomolgus Monkey (Macaca fascicularis) Caudate-Putame...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human Serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed