Affinity DataKi: 3.30nMAssay Description:Inhibitory constant for cytochrome P450 2D6More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of 1'-hydroxybufuralol formation by human liver microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Apparent inhibitory constant (Ki) for Bufuralol 1'-hydroxylation by human liver microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of 1'-hydroxybufuralol formation by human liver microsomesMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of [3H]rauwolscine to CHO cells expressing the human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of partially purified cytochrome P450 2D6 1'-hydroxybufuralol formationMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Inhibition of [3H]rauwolscine binding to CHO cells expressing the human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of 1'-hydroxybufuralol formation by human liver microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of 1'-hydroxybufuralol formation by human liver microsomesMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of [3H]rauwolscine binding to CHO cells expressing the human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 289nMAssay Description:Inhibition of [3H]nitrendipine binding to membrane homogenates of rat cardiac muscle.More data for this Ligand-Target Pair