BDBM50509708 CHEMBL4458648

SMILES S=C(NCc1ccccc1)NNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=GHGXCYPXBDQVRC-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50509708   

TargetAcetylcholinesterase(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509708BDBM50509708(CHEMBL4458648)
Affinity DataKi:  121nMAssay Description:Mixed type inhibition of recombinant human AChE assessed as dissociation constant using acetylthiocholine iodide as substrate incubated for 10 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509708BDBM50509708(CHEMBL4458648)
Affinity DataIC50: 218nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pre-incubated for 20 mins before substrate addition and measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509708BDBM50509708(CHEMBL4458648)
Affinity DataKi:  253nMAssay Description:Mixed type inhibition of recombinant human AChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using acetylthiocholine iodi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509708BDBM50509708(CHEMBL4458648)
Affinity DataIC50: 622nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 10 mins by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed