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Found 58 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [S768I]'
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557850(6-((1-acryloylpiperidin-4-yl)oxy)-4-((3,4-dichloro...)
Affinity DataIC50:  0.130nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557852(1-(3-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  0.350nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557849(1-(3-((4-((3,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  0.510nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM50468247(HM 781-36B | HM-781-36B | NOV-120101 | Poziotinib ...)
Affinity DataIC50:  0.910nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557865(1-(4-((4-((3,4-dichloro- phenyl)amino)-7-methoxy- ...)
Affinity DataIC50:  2nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557851(1-(3-((4-((2,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  2.5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557875(1-(3-((7-methoxy-4- (phenylamino)quinazolin-6- yl)...)
Affinity DataIC50:  2.90nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557870(1-(3-((4-((3,4-dichloro-2- fluorophenyl)amino)-7- ...)
Affinity DataIC50:  3.90nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557858(6-((1-acryloylpiperidin-4- yl)oxy)-4-((4-bromo-3- ...)
Affinity DataIC50:  4nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557868(1-(3-((4-((4-bromo-3- chlorophenyl)amino)-7- metho...)
Affinity DataIC50:  4.80nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557846(1-(4-((4-((2,4-dichlorophenyl)amino)-7-methoxyquin...)
Affinity DataIC50:  5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557872(1-(4-((4-((4-bromo-3- chlorophenyl)amino)-7- metho...)
Affinity DataIC50:  5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557867(1-(4-((7-methoxy-4-((3- (oxazol-5-yl)phenyl)- amin...)
Affinity DataIC50:  6.5nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557898(1-(3-((4-((3,4-dichloro- phenyl)amino)-7-methoxy- ...)
Affinity DataIC50:  6.60nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557869(1-(3-((4-((3-cyclopropyl- phenyl)amino)-7-methoxy-...)
Affinity DataIC50:  8.10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557888(1-(3-((4-((4-bromo-3- chlorophenyl)amino)-7- metho...)
Affinity DataIC50:  10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557854(US11365189, Ex. No. 9)
Affinity DataIC50:  11nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557899(1-(3-((4-((4-chloro-3- (oxazol-5-yl)phenyl)- amino...)
Affinity DataIC50:  14nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557890(1-(4-((4-((3-cyclopropyl- phenyl)amino)-7-methoxy-...)
Affinity DataIC50:  15nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557861(6-((1-acryloylpiperidin-4- yl)oxy)-7-methoxy-4-((3...)
Affinity DataIC50:  19nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557877(1-(3-((7-methoxy-4-((3- (oxazol-5-yl)phenyl)- amin...)
Affinity DataIC50:  20nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557866(1-(3-((7-methoxy-4-((3- (oxazol-5-yl)phenyl)- amin...)
Affinity DataIC50:  20nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557873(1-(4-((7-methoxy-4- (phenylamino)quinazolin-6- yl)...)
Affinity DataIC50:  33nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557878(1-(3-((7-methoxy-4- (phenylamino)quinazolin-6- yl)...)
Affinity DataIC50:  34nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557881(1-(3-((4-((4-bromo-3- chlorophenyl)amino)- pyrido[...)
Affinity DataIC50:  35nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557848(1-(3-((4-((2,4-dichlorophenyl)amino)pyrido[3,4-d]p...)
Affinity DataIC50:  48nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557886(1-(4-((4-((4-chloro-3- (oxazol-5-yl)phenyl)- amino...)
Affinity DataIC50:  53nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557897(1-(3-((4-((4-chloro-3- (oxazol-5-yl)phenyl)- amino...)
Affinity DataIC50:  66nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557860(6-((1-acryloylpiperidin-4- yl)oxy)-4-((4-chloro-3-...)
Affinity DataIC50:  66nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557883(6-((1-acryloylpiperidin-4- yl)oxy)-4-((3-cycloprop...)
Affinity DataIC50:  67nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557880(1-(3-((4-((4-chloro-3- (hydroxymethyl)phenyl)- ami...)
Affinity DataIC50:  69nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557855(6-((1-acryloylpiperidin-4- yl)oxy)-4-((4-chloro-3-...)
Affinity DataIC50:  81nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557882(6-((1-acryloylpiperidin-4- yl)oxy)-4-((3-chloro-4-...)
Affinity DataIC50:  95nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557871(1-(3-((7-methoxy-4-((4- (trifluoromethyl)phenyl)- ...)
Affinity DataIC50:  100nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557887(1-(4-((4-((3-chloro-4- (trifluoromethoxy)phenyl)- ...)
Affinity DataIC50:  110nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557892(1-(4-((4-((4-chloro-3- (hydroxymethyl)phenyl)- ami...)
Affinity DataIC50:  110nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557876(1-(3-((4-((3-chloro-4- (trifluoromethoxy)phenyl)- ...)
Affinity DataIC50:  130nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557874(1-(3-((4-((2,4-dichloro- phenyl)amino)-7-methoxy- ...)
Affinity DataIC50:  130nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557901(1-(3-((4-((4-chloro-3- (hydroxymethyl)phenyl)- ami...)
Affinity DataIC50:  210nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557900(1-(4-((7-methoxy-4-((4- (trifluoromethyl)phenyl)- ...)
Affinity DataIC50:  220nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557895(1-(3-((4-((3-cyclopropyl- phenyl)amino)-7-methoxy-...)
Affinity DataIC50:  250nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557903(1-(3-((4-((3-(hydroxy- methyl)phenyl)amino)-7- met...)
Affinity DataIC50:  490nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557894(1-(3-((4-((3-chloro-4- (trifluoromethoxy)phenyl)- ...)
Affinity DataIC50:  510nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557856(6-((1-acryloylpiperidin-4- yl)oxy)-4-((3-(hydroxy-...)
Affinity DataIC50:  650nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557885(1-(4-((4-((3-(hydroxy- methyl)phenyl)amino)-7- met...)
Affinity DataIC50:  740nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557908(1-(3-((4-((2,4-dichloro- phenyl)amino)pyrido[3,4- ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557896(1-(3-((7-methoxy-4-((4- (trifluoromethyl)phenyl)- ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557864(6-((1-acryloylpiperidin-4- yl)oxy)-7-methoxy-4-((1...)
Affinity DataIC50:  1.80E+3nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557879(1-(3-((7-methoxy-4-((1- methyl-1H-indazol-7-yl)- a...)
Affinity DataIC50:  2.20E+3nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [S768I](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM557907(1-(3-((4-((4-chloro-3-cyclo- propylphenyl)amino)- ...)
Affinity DataIC50:  2.50E+3nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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