SMILES for Proto-oncogene tyrosine-protein kinase receptor Ret [658-1114]

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)[C@H]2CC[C@H](O)CC2)c2c(cnn2c1)C#N |r,wU:24.26,wD:27.30,(-10.77,-.63,;-10,.71,;-9.23,-.63,;-11.34,1.48,;-8.67,1.48,;-7.34,.71,;-6,1.48,;-4.67,.71,;-3.33,1.48,;-2,.71,;-2,-.83,;-.67,-1.6,;.67,-.83,;.67,.71,;-.67,1.48,;2,-1.6,;2,-3.14,;3.33,-3.91,;3.33,-2.37,;4.67,-1.6,;3.33,-.83,;4.67,-3.14,;6,-3.91,;6,-5.45,;7.34,-3.14,;7.34,-1.6,;8.67,-.83,;10,-1.6,;11.34,-.83,;10,-3.14,;8.67,-3.91,;-3.33,3.02,;-2.19,4.05,;-2.82,5.45,;-4.35,5.29,;-4.67,3.79,;-6,3.02,;-.7,3.65,;.79,3.25,)|

BDBM296634

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)c2ccc(OC(F)F)cc2)c2c(cnn2c1)C#N

BDBM296648

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)c2ccc(OC(F)F)nc2)c2c(cnn2c1)C#N

BDBM296669

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)c2ccc(nc2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM296632

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)c2ccc3OCOc3c2)c2c(cnn2c1)C#N

BDBM296631

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)c2ccc3nccnc3c2)c2c(cnn2c1)C#N

BDBM296649

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM296650

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)c2cccnc2)c2c(cnn2c1)C#N

BDBM296633

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)c2cncnc2)c2c(cnn2c1)C#N

BDBM296612

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3CC(F)(F)F)c2c(cnn2c1)C#N

BDBM296611

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3CC(F)F)c2c(cnn2c1)C#N

BDBM296608

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cc[nH]c(=O)c2)c2c(cnn2c1)C#N

BDBM296607

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(=O)[nH]c2)c2c(cnn2c1)C#N

BDBM296559

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(Cl)nn2)c2c(cnn2c1)C#N

BDBM296434

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(F)nc2)c2c(cnn2c1)C#N

BDBM296595

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC(F)(F)F)c(F)c2)c2c(cnn2c1)C#N

BDBM296591

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC(F)(F)F)cc2)c2c(cnn2c1)C#N

BDBM296597

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC(F)F)cc2)c2c(cnn2c1)C#N

BDBM296765

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC(F)F)nc2)c2c(Cl)cnn2c1

BDBM296442

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC(F)F)nc2)c2c(cnn2c1)C#N

BDBM296552

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OCC(F)(F)F)nc2)c2c(cnn2c1)C#N

BDBM296562

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(nc2)C#N)c2c(cnn2c1)C#N

BDBM296549

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(nc2)C(C)(C)C)c2c(cnn2c1)C#N

BDBM296583

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(nc2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM296515

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc3ncccc3c2)c2c(cnn2c1)C#N

BDBM296553

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cccnc2)c2c(cnn2c1)C#N

BDBM296430

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cncc(Cl)c2)c2c(cnn2c1)C#N

BDBM296431

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cncc(F)c2)c2c(cnn2c1)C#N

BDBM296602

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cnccn2)c2c(cnn2c1)C#N

BDBM296568

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cscn2)c2c(cnn2c1)C#N

BDBM296566

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2csnn2)c2c(cnn2c1)C#N

BDBM296599

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2nc(cs2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM296578

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2nc(cs2)C2CC2)c2c(cnn2c1)C#N

BDBM296613

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2nc(no2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM296586

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ncc[nH]2)c2c(cnn2c1)C#N

BDBM296437

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ncccc2C#N)c2c(cnn2c1)C#N

BDBM296439

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ncccc2F)c2c(cnn2c1)C#N

BDBM296615

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ncccn2)c2c(cnn2c1)C#N

BDBM296693

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3S(=O)(=O)CC(F)(F)F)c2c(cnn2c1)C#N

BDBM296690

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3S(=O)(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM296688

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3S(=O)(=O)Cc2ccccc2)c2c(cnn2c1)C#N

BDBM296618

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3[C@@H](c2ccc(Cl)nc2)C(F)(F)F)c2c(cnn2c1)C#N |r|

BDBM296617

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3[C@H](c2ccc(Cl)nc2)C(F)(F)F)c2c(cnn2c1)C#N |r|

BDBM305280

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC2CCCO2)c2c(cnn2c1)C#N

BDBM305282

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC2CCCOC2)c2c(cnn2c1)C#N

BDBM305281

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC2CCOCC2)c2c(cnn2c1)C#N

BDBM305283

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2c(F)cccc2F)c2c(cnn2c1)C#N

BDBM305032

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM305184

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)N2CCCCC2)c2c(cnn2c1)C#N

BDBM305105

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C(C)(C)c2ccc(Cl)cc2)c2c(cnn2c1)C#N

BDBM305104

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C(C)(C)c2ccccc2)c2c(cnn2c1)C#N

BDBM305101

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2CC2)c2c(cnn2c1)C#N

BDBM305110

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)CC(C)(C)c2ccccc2)c2c(cnn2c1)C#N

BDBM305102

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)CC(F)(F)F)c2c(cnn2c1)C#N

BDBM305095

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305109

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)Cc2ccccc2)c2c(cnn2c1)C#N

BDBM305083

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2[nH]c(=O)ccc2F)c2c(cnn2c1)C#N

BDBM305130

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c(F)ccc(F)c2F)c2c(cnn2c1)C#N

BDBM305086

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c(F)cccc2Cl)c2c(cnn2c1)C#N

BDBM305064

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c(F)cccc2F)c2c(cnn2c1)C#N

BDBM305079

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c[nH]ccc2=O)c2c(cnn2c1)C#N

BDBM305080

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(=O)cc[nH]2)c2c(cnn2c1)C#N

BDBM305048

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)cc(F)c2)c2c(cnn2c1)C#N

BDBM305123

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)cc(F)c2Cl)c2c(cnn2c1)C#N

BDBM305039

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305089

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2c(cnn2c1)C#N

BDBM305065

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2F)c2c(cnn2c1)C#N

BDBM305041

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccc(F)c(F)c2)c2c(cnn2c1)C#N

BDBM305076

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM305093

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccc(CO)c2)c2c(cnn2c1)C#N

BDBM305070

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccc(Cl)c2)c2c(cnn2c1)C#N

BDBM305049

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccc(F)c2)c2c(cnn2c1)C#N

BDBM305038

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccc(F)c2F)c2c(cnn2c1)C#N

BDBM305054

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccc(c2)C2CC2)c2c(cnn2c1)C#N

BDBM305013

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N

BDBM305058

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2C#N)c2c(cnn2c1)C#N

BDBM305036

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305051

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2C2CC2)c2c(cnn2c1)C#N

BDBM305128

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2Cl)c2c(cnn2c1)C#N

BDBM305061

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2F)c2c(cnn2c1)C#N

BDBM305060

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2S(C)(=O)=O)c2c(cnn2c1)C#N

BDBM305045

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305097

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccnc2)c2c(cnn2c1)C#N

BDBM305047

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccnn2)c2c(cnn2c1)C#N

BDBM305043

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccncn2)c2c(cnn2c1)C#N

BDBM305044

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cnccn2)c2c(cnn2c1)C#N

BDBM305088

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305116

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2F)c2c(cnn2c1)C#N

BDBM305063

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305062

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305067

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2F)c2c(cnn2c1)C#N

BDBM305069

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccn2)c2c(cnn2c1)C#N

BDBM305035

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NCc2ccccc2)c2c(cnn2c1)C#N

BDBM305239

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305462

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(N)CC2)c2c(cnn2c1)C#N

BDBM305012

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C)(O)CC2)c2c(cnn2c1)C#N

BDBM305228

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C2)NC(=O)c2c(F)cccc2F)c2c(cnn2c1)C#N

BDBM305227

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C2)NC(=O)c2cccc(F)c2F)c2c(cnn2c1)C#N

BDBM305226

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N

BDBM305230

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305229

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(C2)NC(=O)c2ncccc2F)c2c(cnn2c1)C#N

BDBM305202

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)C(=O)NCc2ccccc2)c2c(cnn2c1)C#N

BDBM305201

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM305200

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)N2CCCC2=O)c2c(cnn2c1)C#N

BDBM305278

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM305274

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)c2cccc(F)c2)c2c(cnn2c1)C#N

BDBM305273

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N

BDBM305276

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305277

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)c2cccnc2)c2c(cnn2c1)C#N

BDBM305413

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Nc2ccccc2)c2c(Cl)cnn2c1

BDBM305023

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM305264

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Nc2ccccn2)c2c(cnn2c1)C#N

BDBM305245

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)OCc2ccccc2)c2c(cnn2c1)C#N

BDBM305246

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)OCc2ccccn2)c2c(cnn2c1)C#N

BDBM305255

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(Cl)cc2)c2c(cnn2c1)C#N

BDBM305233

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(Cl)cn2)c2c(cnn2c1)C#N

BDBM305021

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM305237

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(F)cn2)c2c(cnn2c1)C#N

BDBM305243

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(OC(F)F)nc2)c2c(cnn2c1)C#N

BDBM305409

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(cc2)C#N)c2c(Cl)cnn2c1

BDBM305256

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(cc2)C#N)c2c(cnn2c1)C#N

BDBM305238

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(cn2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM305257

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cccc(F)c2)c2c(cnn2c1)C#N

BDBM305022

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccc2)c2c(cnn2c1)C#N

BDBM305258

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccc2F)c2c(cnn2c1)C#N

BDBM305259

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccc2[N+]#[C-])c2c(cnn2c1)C#N

BDBM305410

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(Cl)cnn2c1

BDBM305019

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305020

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cccnc2)c2c(cnn2c1)C#N

BDBM305251

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cccnn2)c2c(cnn2c1)C#N

BDBM305235

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cncc(Cl)c2)c2c(cnn2c1)C#N

BDBM305249

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cncc(F)c2)c2c(cnn2c1)C#N

BDBM305232

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2cnccn2)c2c(cnn2c1)C#N

BDBM305234

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ncc(Cl)cc2F)c2c(cnn2c1)C#N

BDBM305471

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ncccc2F)c2c(cnn2c1)C#N

BDBM305231

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ncccn2)c2c(cnn2c1)C#N

BDBM305204

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305205

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)Cc2ccccc2)c2c(cnn2c1)C#N

BDBM305203

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305207

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305464

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Sc2ccccn2)c2c(cnn2c1)C#N

BDBM305262

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(CC2)c2nc3ccccc3[nH]2)c2c(cnn2c1)C#N

BDBM305247

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(COc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM305025

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305024

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM305467

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(N)CC2)c2c(cnn2c1)C#N

BDBM305747

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(CC2)C(F)c2ccccc2)c2c(cnn2c1)C#N

BDBM305730

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccc(F)cc3)CC2)c2c(cnn2c1)C#N

BDBM305724

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3cccc(F)c3)CC2)c2c(cnn2c1)C#N

BDBM305011

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305726

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccc3F)CC2)c2c(cnn2c1)C#N

BDBM305688

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM305722

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3cccnc3)CC2)c2c(cnn2c1)C#N

BDBM305736

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3cncc(F)c3)CC2)c2c(cnn2c1)C#N

BDBM305735

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3Cl)CC2)c2c(cnn2c1)C#N

BDBM305725

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3F)CC2)c2c(cnn2c1)C#N

BDBM296803

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCCN(CC2)C(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM296805

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM296543

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(N)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM296419

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccc(Cl)cc2)c2c(cnn2c1)C#N |r|

BDBM296421

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccc(F)cc2)c2c(cnn2c1)C#N |r|

BDBM296420

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296426

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(Cl)cn3)CC2)c2c(cnn2c1)C#N

BDBM296751

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)C(=O)C2)c2c(cnn2c1)C#N

BDBM296425

CC(C)(O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM305183

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305187

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2ccc(F)cc2)c2c(cnn2c1)C#N |r|

BDBM305190

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2ccc(F)cn2)c2c(cnn2c1)C#N |r|

BDBM305411

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2ccccn2)c2c(Cl)cnn2c1 |r|

BDBM305185

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305193

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2cncc(F)c2)c2c(cnn2c1)C#N |r|

BDBM305188

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@H](C2)Oc2cnccn2)c2c(cnn2c1)C#N |r|

BDBM305222

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)C2CC2)c2c(cnn2c1)C#N |r|

BDBM305216

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)Cc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305218

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2c(F)cccc2F)c2c(cnn2c1)C#N |r|

BDBM305225

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2cccc(F)c2)c2c(cnn2c1)C#N |r|

BDBM305217

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2cccc(F)c2F)c2c(cnn2c1)C#N |r|

BDBM305215

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305223

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2ccccc2Cl)c2c(cnn2c1)C#N |r|

BDBM305224

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2ccccc2F)c2c(cnn2c1)C#N |r|

BDBM305221

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N |r|

BDBM305220

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@@](C)(C2)NC(=O)c2ncccc2F)c2c(cnn2c1)C#N |r|

BDBM305182

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@H](C2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305412

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@H](C2)Oc2ccccn2)c2c(Cl)cnn2c1 |r|

BDBM305186

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305214

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)C2CC2)c2c(cnn2c1)C#N |r|

BDBM305209

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)Cc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305211

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)c2c(F)cccc2F)c2c(cnn2c1)C#N |r|

BDBM305210

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)c2cccc(F)c2F)c2c(cnn2c1)C#N |r|

BDBM305208

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305213

CC(C)(O)COc1cc(-c2ccc(nc2)N2CC[C@](C)(C2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N |r|

BDBM305466

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3N)c2c(cnn2c1)C#N |r|

BDBM305465

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305271

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3NC(=O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305272

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3NC(=O)c2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305267

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3Nc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305268

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3Nc2ncccc2Cl)c2c(cnn2c1)C#N |r|

BDBM305265

CC(C)(O)COc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3Nc2ncccn2)c2c(cnn2c1)C#N |r|

BDBM296760

CC(C)(O)COc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2ccc(OC(F)F)nc2)c2c(cnn2c1)C#N

BDBM305769

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2c(F)ccc(F)c2F)c2c(cnn2c1)C#N

BDBM305771

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305766

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2c(cnn2c1)C#N

BDBM305770

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305767

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305751

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(O)(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM305745

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(O)(Cc3ncccc3Cl)CC2)c2c(cnn2c1)C#N

BDBM305750

CC(C)(O)COc1cc(-c2cnc(cn2)N2CCC(O)(Cc3ncccc3F)CC2)c2c(cnn2c1)C#N

BDBM296621

CC(C)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284211

CC(C)C(=O)N1CC2(C1)CCN(CC2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296799

CC(C)C(=O)N1CCC11CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM284203

CC(C)C(=O)N1CCC2(C1)CCCN(C2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284197

CC(C)C(=O)N1CCC2(C1)CCN(CC2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284056

CC(C)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305014

CC(C)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305006

CC(C)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM284193

CC(C)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305275

CC(C)C(=O)NC1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284175

CC(C)C(=O)NC1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284216

CC(C)C(=O)N[C@@H]1CCCN(C1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284215

CC(C)C(=O)N[C@H]1CCCN(C1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284019

CC(C)C(C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1

BDBM284150

CC(C)C(O)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284615

CC(C)C(O)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(Cl)c12)-c1cnn(C)c1

BDBM284380

CC(C)C1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296626

CC(C)CC(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296358

CC(C)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCN(C)CC2)cn2ncc(C#N)c12

BDBM296354

CC(C)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM296365

CC(C)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCn2ccnc2)cn2ncc(C#N)c12

BDBM296363

CC(C)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCc2cccnc2)cn2ncc(C#N)c12

BDBM284263

CC(C)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1ccn(C)n1

BDBM284065

CC(C)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284257

CC(C)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(c1)C(F)F

BDBM284613

CC(C)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(Cl)c12)-c1cnn(C)c1

BDBM284273

CC(C)CC(=O)N1CCN(CC1)c1ncc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305652

CC(C)CC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305005

CC(C)CC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM305715

CC(C)CC(=O)NC1(C)CCN(CC1)c1cnc(nc1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM284234

CC(C)CN(C)C(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284383

CC(C)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305279

CC(C)CNC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305655

CC(C)CNC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM296682

CC(C)CNC(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM315475

CC(C)CNC(=O)N1CCN(CC1)c1ccc(cc1)-c1cc(OC[C@@H](C)O)cn2ncc(C#N)c12 |r|

BDBM296423

CC(C)CNC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296457

CC(C)CNC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCCO)cn2ncc(C#N)c12

BDBM296372

CC(C)CNC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM296393

CC(C)CNC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OC[C@@H](C)O)cn2ncc(C#N)c12 |r|

BDBM296397

CC(C)CNC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OC[C@H](C)O)cn2ncc(C#N)c12 |r|

BDBM284123

CC(C)CNC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305010

CC(C)CNC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM296680

CC(C)COC(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284627

CC(C)COC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305651

CC(C)COC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305007

CC(C)COC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM284187

CC(C)COC1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296341

CC(C)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM296342

CC(C)COc1cc(-c2ccc(nc2)N2CCN(Cc3ncccn3)CC2)c2c(cnn2c1)C#N

BDBM305033

CC(C)CS(=O)(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296691

CC(C)CS(=O)(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296545

CC(C)CS(=O)(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284080

CC(C)CS(=O)(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296541

CC(C)C[C@@H](CN(C)C)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM296540

CC(C)C[C@@H](CN)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM296674

CC(C)C[C@@H](N(C)C)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM296539

CC(C)C[C@@H](N(C)C)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM296673

CC(C)C[C@@H](N)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM296538

CC(C)C[C@@H](N)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM284043

CC(C)C[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284046

CC(C)C[C@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284584

CC(C)Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284237

CC(C)N(C)C(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284546

CC(C)N(CCO)C(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284576

CC(C)N1CC(C1)n1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284400

CC(C)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284241

CC(C)NC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305016

CC(C)NC(=O)C1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284236

CC(C)NC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284557

CC(C)NC(=O)C1CN(C1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284239

CC(C)NC(=O)CC1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284559

CC(C)NC(=O)CC1CN(C1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284134

CC(C)NC(=O)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296380

CC(C)NC(=O)N1CC2(C1)CCN(CC2)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM284116

CC(C)NC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305009

CC(C)NC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM284177

CC(C)NC(=O)NC1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284219

CC(C)NC(=O)[C@@H]1CCCN(C1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284251

CC(C)NC(=O)[C@@H]1CCN(C1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284218

CC(C)NC(=O)[C@@H]1CN(CCO1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284220

CC(C)NC(=O)[C@H]1CCCN(C1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284254

CC(C)NC(=O)[C@H]1CCN(C1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284217

CC(C)NC(=O)[C@H]1CN(CCO1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284554

CC(C)NS(=O)(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296381

CC(C)OC(=O)N1CC2(C1)CCN(CC2)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM284212

CC(C)OC(=O)N1CC2(C1)CCN(CC2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305647

CC(C)OC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OC(=O)N(C)C)cn2ncc(C#N)c12

BDBM305650

CC(C)OC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305648

CC(C)OC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCn2ccnc2)cn2ncc(C#N)c12

BDBM305649

CC(C)OC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCc2cn(C)cn2)cn2ncc(C#N)c12

BDBM284178

CC(C)OC(=O)NC1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305157

CC(C)OC1CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296610

CC(C)OCCN1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284600

CC(C)OCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cc(C)n[nH]1

BDBM284601

CC(C)OCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cc(C)no1

BDBM284568

CC(C)OCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1ccn(C)n1

BDBM284604

CC(C)OCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnc(C)o1

BDBM284382

CC(C)OCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284566

CC(C)OCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(c1)C(F)F

BDBM284224

CC(C)OCCNC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305244

CC(C)OCCOC1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296496

CC(C)OCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM296500

CC(C)OCCOc1cc(-c2ccc(nc2)N2CCN(CC3CCOCC3)CC2)c2c(cnn2c1)C#N

BDBM296200

CC(C)OCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM296499

CC(C)OCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ncccn3)CC2)c2c(cnn2c1)C#N

BDBM296497

CC(C)OCCOc1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM284097

CC(C)O[C@@H]1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284098

CC(C)O[C@H]1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM296197

CC(C)Oc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM296548

CC(C)Oc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM284634

CC(C)Oc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM296638

CC(C)Oc1ccc(cc1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284393

CC(C)S(=O)(=O)CCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305654

CC(C)[C@@H](C)NC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12 |r|

BDBM284206

CC(C)[C@@H](O)C(=O)N1CC2(C1)CCN(CC2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284200

CC(C)[C@@H](O)C(=O)N1CCC2(C1)CCCN(C2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284196

CC(C)[C@@H](O)C(=O)N1CCC2(C1)CCN(CC2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM296455

CC(C)[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCCO)cn2ncc(C#N)c12 |r|

BDBM296360

CC(C)[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCN(C)CC2)cn2ncc(C#N)c12 |r|

BDBM296356

CC(C)[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12 |r|

BDBM296370

CC(C)[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12 |r|

BDBM284692

CC(C)[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cn(C)nn1 |r|

BDBM284694

CC(C)[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cn(nn1)C(C)C |r|

BDBM284688

CC(C)[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnc(C)s1 |r|

BDBM284075

CC(C)[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284275

CC(C)[C@@H](O)C(=O)N1CCN(CC1)c1ncc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM305008

CC(C)[C@@H](O)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12 |r|

BDBM305653

CC(C)[C@H](C)NC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12 |r|

BDBM296456

CC(C)[C@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCCO)cn2ncc(C#N)c12 |r|

BDBM296371

CC(C)[C@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12 |r|

BDBM284044

CC(C)[C@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM296577

CC(C)c1cc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)no1

BDBM296579

CC(C)c1csc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1

BDBM296567

CC(C)n1cc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM284435

CC(C)n1cc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM284586

CC(C)n1cc(c(C)n1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284583

CC(C)n1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305138

CC(C)n1cc(cn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284693

CC(C)n1cc(nn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284696

CC(C)n1cc(nn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM284697

CC(C)n1cc(nn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ncccn3)CC2)c2c(cnn2c1)C#N

BDBM284235

CC(O)CN(C)C(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM315530

CC(O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccc(Cl)cc2)c2c(cnn2c1)C#N

BDBM305470

CC1(CCN(CC1)c1ccc(cn1)-c1cc(O)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305445

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305662

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305442

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCC2CNC2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305415

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCCN2CCCC2)cn2ncc(C#N)c12)NC(=O)c1ncc(F)cc1Cl

BDBM305423

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ccccc1

BDBM305438

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305416

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ncc(F)cc1Cl

BDBM305305

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305422

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCCC2)cn2ncc(C#N)c12)NC(=O)c1ccccc1

BDBM305441

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCCC2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305303

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCCC2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305420

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ccccc1

BDBM305436

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305301

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305307

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCNCC(F)F)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305439

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OCCn2ccnc2)cn2ncc(C#N)c12)NC(=O)c1ccccn1

BDBM305659

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OC[C@@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl |r|

BDBM305658

CC1(CCN(CC1)c1ccc(cn1)-c1cc(OC[C@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl |r|

BDBM305685

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12)NC(=O)c1cc(F)ccc1Cl

BDBM305772

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305677

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl

BDBM305782

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OC[C@@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl |r|

BDBM305781

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OC[C@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1cc(F)ccc1C(F)(F)F |r|

BDBM305780

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OC[C@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1ncc(F)cc1Cl |r|

BDBM305779

CC1(CCN(CC1)c1cnc(cn1)-c1cc(OC[C@H]2CNCCO2)cn2ncc(C#N)c12)NC(=O)c1ncccc1Cl |r|

BDBM305666

CC1(CCN(CC1)c1ncc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12)NC(=O)c1cc(F)ccc1Cl

BDBM296198

CC1(COc2cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c3c(cnn3c2)C#N)COC1

BDBM296353

CC1(COc2cc(-c3ccc(nc3)N3CCN(Cc4ccccn4)CC3)c3c(cnn3c2)C#N)COC1

BDBM305004

CC1(N)CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12

BDBM315485

CC1=NC(=CC(=O)C1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |c:3,t:1|

BDBM284057

CCC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305100

CCC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284053

CCC(C)(O)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296347

CCC(C)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM296346

CCC(C)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM296345

CCC(C)COc1cc(-c2ccc(nc2)N2CCN(Cc3ncccn3)CC2)c2c(cnn2c1)C#N

BDBM296517

CCC(C)S(=O)(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284483

CCC(CC)C(=O)N1CC2(C1)CCN(CC2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296349

CCC(CC)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM296348

CCC(CC)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM304971

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(OC)cn2ncc(C#N)c12)C(=O)NC(C)C

BDBM305263

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12)C(=O)NCC(C)C

BDBM305206

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12)C(=O)Nc1ccccc1

BDBM284579

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cn(C)nc1C)C(=O)NC(C)C

BDBM284246

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)C(=O)NC(C)C

BDBM284248

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)C(=O)NCC(C)(C)O

BDBM284245

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)C(=O)NCCC(F)(F)F

BDBM284247

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)C(=O)N[C@H](C)C(F)(F)F |r|

BDBM284577

CCC1(CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1C)C(=O)NC(C)C

BDBM284379

CCC1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284060

CCCC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305567

CCCC(=O)NC1(CN2CCOCC2)CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM284367

CCCCN(C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1

BDBM284660

CCCN1C2CC1CN(C2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284398

CCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305340

CCCO[C@@H]1CN(C[C@H]1N)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12 |r|

BDBM305335

CCCO[C@H]1CN(C[C@@H]1N)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12 |r|

BDBM303296

CCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM296338

CCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM296340

CCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ncccn3)CC2)c2c(cnn2c1)C#N

BDBM296534

CCCOc1ccc(cn1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM284357

CCCc1onc(C)c1C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296535

CCCn1cc(ccc1=O)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM284126

CCN(C)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284489

CCN(CC)C(=O)N1CC2(C1)CCN(CC2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284088

CCN(CC)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284354

CCN(CC)C(C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1

BDBM305684

CCN1CC(F)(COc2cc(-c3cnc(cn3)N3CCC(C)(CC3)NC(=O)c3c(C)cccc3Cl)c3c(cnn3c2)C#N)C1

BDBM305686

CCN1CC(F)(COc2cc(-c3cnc(cn3)N3CCC(C)(CC3)NC(=O)c3cc(F)ccc3Cl)c3c(cnn3c2)C#N)C1

BDBM284602

CCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnc(C)o1

BDBM284399

CCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305426

CCN1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccc3)c3c(cnn3c2)C#N)CC1

BDBM305681

CCN1CCN(CCOc2cc(-c3cnc(cn3)N3CCC(C)(CC3)NC(=O)c3c(C)cccc3Cl)c3c(cnn3c2)C#N)CC1

BDBM305671

CCN1CCO[C@@H](COc2cc(-c3cnc(cn3)N3CCC(C)(CC3)NC(=O)c3c(C)cccc3Cl)c3c(cnn3c2)C#N)C1 |r|

BDBM305673

CCN1CCO[C@H](COc2cc(-c3cnc(cn3)N3CCC(C)(CC3)NC(=O)c3c(C)cccc3Cl)c3c(cnn3c2)C#N)C1 |r|

BDBM284124

CCNC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305640

CCOC(=O)C1(CO)CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM305490

CCOC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM305540

CCOC(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM305582

CCOC(=O)NC1(CN2CCN(CC)CC2)CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM305575

CCOC(=O)NC1(CN2CCOCC2)CCN(CC1)c1ccc(cn1)-c1cc(OCC)cn2ncc(C#N)c12

BDBM284659

CCOCCN1C2CC1CN(C2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284603

CCOCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnc(C)o1

BDBM284387

CCOCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296199

CCOCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284227

CCONC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305644

CCOc1cc(-c2ccc(cc2)N2CCC(CN(C)C)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM296332

CCOc1cc(-c2ccc(nc2)N2C3CC2CN(Cc2ccc(OC)nc2)C3)c2c(cnn2c1)C#N

BDBM296333

CCOc1cc(-c2ccc(nc2)N2C3CCC2CN(Cc2ccc(OC)nc2)C3)c2c(cnn2c1)C#N

BDBM304999

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)C3N)c2c(cnn2c1)C#N

BDBM304995

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)C3O)c2c(cnn2c1)C#N

BDBM304996

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)C3OCCOC)c2c(cnn2c1)C#N

BDBM296532

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)C(CN(C)C)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM296526

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)C(CN)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM296531

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)C(N(C)C)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM296525

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)C(N)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM430529

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)[C@H](N(C)C)c2cccc(Cl)c2)c2c(cnn2c1)C#N |r|

BDBM296240

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)[C@H](O)c2ccc(F)cc2)c2c(cnn2c1)C#N |r|

BDBM296239

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)[C@H](OC)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296533

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)c2ccc(O)nc2)c2c(cnn2c1)C#N

BDBM296536

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)c2ccc(OCCOC)nc2)c2c(cnn2c1)C#N

BDBM296252

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cc(C)nc(C)c2)c2c(cnn2c1)C#N

BDBM296254

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cc(OC)ccn2)c2c(cnn2c1)C#N

BDBM296245

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(C)nc2)c2c(cnn2c1)C#N

BDBM296249

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(Cl)nc2)c2c(cnn2c1)C#N

BDBM296253

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(F)cn2)c2c(cnn2c1)C#N

BDBM296241

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c(cnn2c1)C#N

BDBM296255

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cccc(C)n2)c2c(cnn2c1)C#N

BDBM296256

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cccc(OC)n2)c2c(cnn2c1)C#N

BDBM296251

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccccn2)c2c(cnn2c1)C#N

BDBM296244

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cccnc2)c2c(cnn2c1)C#N

BDBM296248

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccnc(C)c2)c2c(cnn2c1)C#N

BDBM296330

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cnc(OC)c(Cl)c2)c2c(cnn2c1)C#N

BDBM296246

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cncc(C)c2)c2c(cnn2c1)C#N

BDBM296242

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cncc(Cl)c2)c2c(cnn2c1)C#N

BDBM296243

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cncc(F)c2)c2c(cnn2c1)C#N

BDBM296250

CCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2cncc(OC)c2)c2c(cnn2c1)C#N

BDBM305000

CCOc1cc(-c2ccc(nc2)N2CC3C[C@@H](C2)[C@@H]3Nc2ccc(OC)nc2)c2c(cnn2c1)C#N |r|

BDBM304998

CCOc1cc(-c2ccc(nc2)N2CC3C[C@@H](C2)[C@H]3Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM304997

CCOc1cc(-c2ccc(nc2)N2CC3C[C@@H](C2)[C@H]3Oc2ncccn2)c2c(cnn2c1)C#N |r|

BDBM305450

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)N2CCCC2)c2c(cnn2c1)C#N

BDBM305449

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305451

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305460

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC(F)(F)F)c2c(cnn2c1)C#N

BDBM305457

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCC2CC2)c2c(cnn2c1)C#N

BDBM305461

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NC[C@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305459

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)N[C@@H](C)C(C)C)c2c(cnn2c1)C#N |r|

BDBM305458

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)N[C@H](C)C(C)C)c2c(cnn2c1)C#N |r|

BDBM305455

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccc(C)cn2)c2c(cnn2c1)C#N

BDBM305454

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccc(C)nc2)c2c(cnn2c1)C#N

BDBM305452

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccc(OC)nc2)c2c(cnn2c1)C#N

BDBM305352

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM305456

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2ccccn2)c2c(cnn2c1)C#N

BDBM305453

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)Nc2cccnc2)c2c(cnn2c1)C#N

BDBM305526

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(C)CCC2)c2c(cnn2c1)C#N

BDBM305519

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305524

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCC2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM305529

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCC2)N(C)C)c2c(cnn2c1)C#N

BDBM305520

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305534

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCCC2)N(C)C)c2c(cnn2c1)C#N

BDBM305517

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCCC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305528

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCOCC2)N(C)C)c2c(cnn2c1)C#N

BDBM305523

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(CCOCC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305531

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(N)CC2)c2c(cnn2c1)C#N

BDBM315892

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(N)CCC2)c2c(cnn2c1)C#N

BDBM305527

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(N)CCCC2)c2c(cnn2c1)C#N

BDBM315891

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(N)CCOCC2)c2c(cnn2c1)C#N

BDBM305525

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)C2(O)CC2)c2c(cnn2c1)C#N

BDBM305434

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305433

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305429

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305435

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305543

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC2CCC2)c2c(cnn2c1)C#N

BDBM305539

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC2CCCC2)c2c(cnn2c1)C#N

BDBM305541

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OCC(C)C)c2c(cnn2c1)C#N

BDBM305538

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OCC2CC2)c2c(cnn2c1)C#N

BDBM305542

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)O[C@H]2CCOC2)c2c(cnn2c1)C#N |r|

BDBM305530

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@@H](N)CC)c2c(cnn2c1)C#N |r|

BDBM315896

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@@H]2CCN2)c2c(cnn2c1)C#N |r|

BDBM305522

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@@H]2CCN2C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305533

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@@H]2CCN2C)c2c(cnn2c1)C#N |r|

BDBM305521

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305532

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@H](C)NC)c2c(cnn2c1)C#N |r|

BDBM305518

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)[C@H](CC)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305430

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305431

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cccnc2)c2c(cnn2c1)C#N

BDBM305302

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305432

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NCc2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305516

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)Nc2nc(C)ccc2F)c2c(cnn2c1)C#N

BDBM305515

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)OC(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305355

CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)S(=O)(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305469

CCOc1cc(-c2ccc(nc2)N2CCC(C)(N)CC2)c2c(cnn2c1)C#N

BDBM305354

CCOc1cc(-c2ccc(nc2)N2CCC(CC)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305353

CCOc1cc(-c2ccc(nc2)N2CCC(CC)(CC2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM305491

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)OC(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305315

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(C)nn2)c2c(cnn2c1)C#N

BDBM305316

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(Cl)nc2)c2c(cnn2c1)C#N

BDBM305308

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(OC)nn2)c2c(cnn2c1)C#N

BDBM305317

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(OCCO)nc2)c2c(cnn2c1)C#N

BDBM304993

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM304994

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ncccn2)c2c(cnn2c1)C#N

BDBM305358

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)Cc2ccccc2)c2c(cnn2c1)C#N

BDBM305492

CCOc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305594

CCOc1cc(-c2ccc(nc2)N2CCC(CCNC3CCN(C)CC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305561

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305552

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)C(C)C(C)C)c2c(cnn2c1)C#N

BDBM305368

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305551

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)CC2(CC2)OC)c2c(cnn2c1)C#N

BDBM305369

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305559

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)N2CCCC2)c2c(cnn2c1)C#N

BDBM305560

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)N2CCCCC2)c2c(cnn2c1)C#N

BDBM305370

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305558

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305556

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)OCC(C)(C)C)c2c(cnn2c1)C#N

BDBM305555

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)OCC(C)C)c2c(cnn2c1)C#N

BDBM305557

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)OCC2CC2)c2c(cnn2c1)C#N

BDBM305366

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305554

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)c2ncccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305367

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305553

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)C)(CC2)NC(=O)c2ncccc2F)c2c(cnn2c1)C#N

BDBM305618

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CC(=O)N(C)C)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305596

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CC(C)(C)O)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305365

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CC(F)(F)CO)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305598

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CC(F)F)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305363

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CCCO)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305617

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CCN(C)C)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305616

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CCO)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305626

CCOc1cc(-c2ccc(nc2)N2CCC(CN(C)CCOC)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305597

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC(C)(O)C3)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305623

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC(C3)N(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305625

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC(C3)OC)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305629

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC(F)(F)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305622

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC4(CN(C)C4)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305635

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC4CC(C3)N4)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305621

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC4CC(C3)N4C(=O)OC(C)(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305624

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCC(F)(F)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305599

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCC(F)(F)C3)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305562

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305564

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCCC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305563

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCCC3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305632

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C(=O)OC(C)(C)C)C(C)(C)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305593

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)CC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305638

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)[C@@H](C)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305585

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)[C@@H](C)C3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N |r|

BDBM305589

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)[C@@H](C)C3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N |r|

BDBM305590

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)[C@@H](C)C3)(CC2)NC(=O)Oc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM305586

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C)[C@@H](C)C3)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N |r|

BDBM305637

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)C(C)(C)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305584

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305577

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)C(C)C(C)C)c2c(cnn2c1)C#N

BDBM305578

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)C(C)C)c2c(cnn2c1)C#N

BDBM305377

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305376

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305378

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM305379

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305583

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305375

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)OC)c2c(cnn2c1)C#N

BDBM305580

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2cc(Cl)cnc2C)c2c(cnn2c1)C#N

BDBM305372

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305374

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2cc(F)ccc2F)c2c(cnn2c1)C#N

BDBM305579

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305373

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2ncccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305581

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)CC3)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305636

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC)[C@H](C)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305591

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CC3)C(=O)OC(C)(C)C)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305595

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(CCOC)CC3)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305619

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN(C[C@@H]3C)C(=O)OC(C)(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305630

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN([C@@H](C)C3)C(=O)OC(C)(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305587

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN([C@@H](C)C3)C(=O)OC(C)(C)C)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N |r|

BDBM305631

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN([C@H](C)C3)C(=O)OC(C)(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305592

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCNCC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305634

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCNC[C@@H]3C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305633

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN[C@@H](C)C3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305588

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCN[C@@H](C)C3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N |r|

BDBM305380

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305570

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)C(C)C(C)C)c2c(cnn2c1)C#N

BDBM305573

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)C2(CC2)OC)c2c(cnn2c1)C#N

BDBM305571

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC(C)(C)O)c2c(cnn2c1)C#N

BDBM305572

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC(C)(C)OC)c2c(cnn2c1)C#N

BDBM305569

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC(C)C(F)(F)F)c2c(cnn2c1)C#N

BDBM305565

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305568

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC(F)(F)F)c2c(cnn2c1)C#N

BDBM305566

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC)c2c(cnn2c1)C#N

BDBM305371

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM305574

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)C[C@@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305576

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305362

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305381

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CCOCC3)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305627

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC[C@@H](C3)OC)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305628

CCOc1cc(-c2ccc(nc2)N2CCC(CN3CC[C@H](C3)OC)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305620

CCOc1cc(-c2ccc(nc2)N2CCC(CNC3CCOCC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305364

CCOc1cc(-c2ccc(nc2)N2CCC(CNCC(C)(C)O)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305639

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305325

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2c(F)cccc2F)c2c(cnn2c1)C#N

BDBM305324

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM315689

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2ncccc2C#N)c2c(cnn2c1)C#N

BDBM305327

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(CC2)NC(=O)c2ncccc2F)c2c(cnn2c1)C#N

BDBM305323

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(Cc3ccc(OC)cc3)CC2)c2c(cnn2c1)C#N

BDBM305320

CCOc1cc(-c2ccc(nc2)N2CCC(CO)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305321

CCOc1cc(-c2ccc(nc2)N2CCC(COC)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305322

CCOc1cc(-c2ccc(nc2)N2CCC(COCC(=O)N(C)C)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305642

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN(C)C)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305641

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN3CCOCC3)(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM305545

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN3CCOCC3)(CC2)NC(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM305546

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN3CCOCC3)(CC2)NC(=O)c2cccc(Cl)n2)c2c(cnn2c1)C#N

BDBM305547

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN3CCOCC3)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305548

CCOc1cc(-c2ccc(nc2)N2CCC(COCCN3CCOCC3)(CC2)NS(=O)(=O)c2ccc(C)cc2)c2c(cnn2c1)C#N

BDBM305794

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)C(C)(C)O)c2c(cnn2c1)C#N

BDBM305319

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)CC(C)(C)O)c2c(cnn2c1)C#N

BDBM305318

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)CCO)c2c(cnn2c1)C#N

BDBM305796

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)CN(C)C)c2c(cnn2c1)C#N

BDBM305789

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)CO)c2c(cnn2c1)C#N

BDBM305790

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)C[C@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305792

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@@H](C)OC)c2c(cnn2c1)C#N |r|

BDBM305798

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@@H](N)C(C)C)c2c(cnn2c1)C#N |r|

BDBM305797

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@@H](N)[C@@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305800

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@@H]2[C@@H](O)CCN2CC)c2c(cnn2c1)C#N |r|

BDBM305791

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305795

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@H](O)CO)c2c(cnn2c1)C#N |r|

BDBM305793

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@H]2CCCN2C)c2c(cnn2c1)C#N |r|

BDBM305799

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@H]2NCC[C@@H]2O)c2c(cnn2c1)C#N |r|

BDBM305356

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)(CC2)NC(C)=O)c2c(cnn2c1)C#N

BDBM305607

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)N(C)C)c2c(cnn2c1)C#N

BDBM305610

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CC2CN(CC)CCO2)c2c(cnn2c1)C#N

BDBM305608

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CC2CNC2)c2c(cnn2c1)C#N

BDBM305609

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CC2CNCCO2)c2c(cnn2c1)C#N

BDBM305613

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CCN2CCOCC2)c2c(cnn2c1)C#N

BDBM305601

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CN(C)C)c2c(cnn2c1)C#N

BDBM305603

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CN2CCCCC2)c2c(cnn2c1)C#N

BDBM305606

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)CN2CCOCC2)c2c(cnn2c1)C#N

BDBM305600

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)Cc2nccn2C)c2c(cnn2c1)C#N

BDBM305612

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@@H](C)N)c2c(cnn2c1)C#N |r|

BDBM305605

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@@H](C)OC)c2c(cnn2c1)C#N |r|

BDBM305615

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@@H](N)C(C)C)c2c(cnn2c1)C#N |r|

BDBM305611

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@@H](N)[C@@H](C)O)c2c(cnn2c1)C#N |r|

BDBM305614

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@H](N)C(C)C)c2c(cnn2c1)C#N |r|

BDBM305801

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@H](O)CO)c2c(cnn2c1)C#N |r|

BDBM305602

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)[C@H]2CCCN2C)c2c(cnn2c1)C#N |r|

BDBM305604

CCOc1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)(CC2)NC(=O)c2cncn2C)c2c(cnn2c1)C#N

BDBM305544

CCOc1cc(-c2ccc(nc2)N2CCC(N)(COCCN3CCOCC3)CC2)c2c(cnn2c1)C#N

BDBM305357

CCOc1cc(-c2ccc(nc2)N2CCC(N)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305311

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CC2)c2ccccc2)c2c(cnn2c1)C#N

BDBM305312

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CC2)c2ccccn2)c2c(cnn2c1)C#N

BDBM305313

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CC2)c2cccnc2)c2c(cnn2c1)C#N

BDBM305314

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CC2)c2ccncc2)c2c(cnn2c1)C#N

BDBM305310

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CCc3cccnc3)CC2)c2c(cnn2c1)C#N

BDBM305549

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CNS(=O)(=O)c3ccc(C)cc3)CC2)c2c(cnn2c1)C#N

BDBM305550

CCOc1cc(-c2ccc(nc2)N2CCC(O)(CNS(=O)(=O)c3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305737

CCOc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM305738

CCOc1cc(-c2ccc(nc2)N2CCC(O)(Cc3cccc(F)c3)CC2)c2c(cnn2c1)C#N

BDBM305309

CCOc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305028

CCOc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM305463

CCOc1cc(-c2ccc(nc2)N2CCC(O)CC2)c2c(cnn2c1)C#N

BDBM296782

CCOc1cc(-c2ccc(nc2)N2CCC3(C2)CCCN(C3)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM296784

CCOc1cc(-c2ccc(nc2)N2CCC3(C2)CCCN(C3)c2ccc(OC)nc2)c2c(cnn2c1)C#N

BDBM296783

CCOc1cc(-c2ccc(nc2)N2CCC3(C2)CCCNC3)c2c(cnn2c1)C#N

BDBM305643

CCOc1cc(-c2ccc(nc2)N2CCC3(CC(C3)NC(=O)OC(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM296778

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3C(=O)c3ccc(F)cc3)CC2)c2c(cnn2c1)C#N

BDBM296779

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3C(=O)c3ccc(OC)cc3)CC2)c2c(cnn2c1)C#N

BDBM296780

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3C(=O)c3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM296781

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3C(=O)c3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM296773

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3S(=O)(=O)c3ccc(C)cc3)CC2)c2c(cnn2c1)C#N

BDBM296775

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3S(=O)(=O)c3ccc(F)cc3)CC2)c2c(cnn2c1)C#N

BDBM296777

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3S(=O)(=O)c3ccc(OC)cc3)CC2)c2c(cnn2c1)C#N

BDBM296776

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3S(=O)(=O)c3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM296774

CCOc1cc(-c2ccc(nc2)N2CCC3(CN3S(=O)(=O)c3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM304989

CCOc1cc(-c2ccc(nc2)N2CCC[C@@H](C2)N(C)C)c2c(cnn2c1)C#N |r|

BDBM304980

CCOc1cc(-c2ccc(nc2)N2CCC[C@@H](C2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM304988

CCOc1cc(-c2ccc(nc2)N2CCC[C@@H](C2)NC)c2c(cnn2c1)C#N |r|

BDBM305328

CCOc1cc(-c2ccc(nc2)N2CCC[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305329

CCOc1cc(-c2ccc(nc2)N2CCC[C@H](C2)N(C)C)c2c(cnn2c1)C#N |r|

BDBM305330

CCOc1cc(-c2ccc(nc2)N2CCC[C@H](C2)NCc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM304987

CCOc1cc(-c2ccc(nc2)N2CCC[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM296529

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(CN(C)C)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM296522

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(CN)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM296528

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(N(C)C)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM296521

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(N)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM296225

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)c2ccccn2)c2c(cnn2c1)C#N

BDBM296228

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(COC)CC2)c2c(cnn2c1)C#N

BDBM296224

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2ccc(F)cn2)c2c(cnn2c1)C#N

BDBM430310

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM296222

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM296530

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H](CC(C)C)N(C)C)c2c(cnn2c1)C#N |r|

BDBM296231

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H](O)C(C)C)c2c(cnn2c1)C#N |r|

BDBM296233

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296230

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H](OC)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296527

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](N(C)C)c2cccc(Cl)c2)c2c(cnn2c1)C#N |r|

BDBM296519

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](N)CC(C)C)c2c(cnn2c1)C#N |r|

BDBM296520

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](N)c2cccc(Cl)c2)c2c(cnn2c1)C#N |r|

BDBM296229

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)C(C)C)c2c(cnn2c1)C#N |r|

BDBM296226

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccc(F)cc2)c2c(cnn2c1)C#N |r|

BDBM296232

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296227

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](OC)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296769

CCOc1cc(-c2ccc(nc2)N2CCN(CC2)c2ccc(OC)nc2)c2c(cnn2c1)C#N

BDBM296236

CCOc1cc(-c2ccc(nc2)N2CCN(CC3CCOCC3)CC2)c2c(cnn2c1)C#N

BDBM296339

CCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM296196

CCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM296237

CCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM296238

CCOc1cc(-c2ccc(nc2)N2CCN(Cc3ncccn3)CC2)c2c(cnn2c1)C#N

BDBM296223

CCOc1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM305331

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](C)[C@H](C2)NC)c2c(cnn2c1)C#N |r|

BDBM305783

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](CN)C2)c2c(cnn2c1)C#N |r|

BDBM305786

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](CNC(=O)CC(C)C)C2)c2c(cnn2c1)C#N |r|

BDBM305785

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](CNC(=O)c3ncccc3Cl)C2)c2c(cnn2c1)C#N |r|

BDBM305349

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305494

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](N)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305504

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)CC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305714

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)CC(C)C)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305493

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)OC(C)(C)C)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305499

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)OC(C)(C)C)[C@@H](C2)OCCN(C)C)c2c(cnn2c1)C#N |r|

BDBM305498

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)OC(C)(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305495

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)OC(C)(C)C)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305513

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)OC(C)C)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305510

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)c3ncccc3Cl)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305512

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](NC(=O)c3ncccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM304992

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](O)[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305698

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](OCCOC(C)C)[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305695

CCOc1cc(-c2ccc(nc2)N2CC[C@@H](Oc3ccc(C)nn3)[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM296334

CCOc1cc(-c2ccc(nc2)N2CC[C@@H]3CCN([C@@H]3C2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM296335

CCOc1cc(-c2ccc(nc2)N2CC[C@@H]3CCN[C@@H]3C2)c2c(cnn2c1)C#N |r|

BDBM296794

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(C)C3)c2c(cnn2c1)C#N |r|

BDBM296787

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(C3)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM296789

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(C3)C(C)=O)c2c(cnn2c1)C#N |r|

BDBM296796

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(C3)C(C)C)c2c(cnn2c1)C#N |r|

BDBM296791

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(C3)C2CC2)c2c(cnn2c1)C#N |r|

BDBM296795

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCN(CC)C3)c2c(cnn2c1)C#N |r|

BDBM296788

CCOc1cc(-c2ccc(nc2)N2CC[C@@]3(C2)CCCNC3)c2c(cnn2c1)C#N |r|

BDBM304990

CCOc1cc(-c2ccc(nc2)N2CC[C@H](C)[C@@H](C2)N(C)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM304991

CCOc1cc(-c2ccc(nc2)N2CC[C@H](C)[C@@H](C2)NC)c2c(cnn2c1)C#N |r|

BDBM305784

CCOc1cc(-c2ccc(nc2)N2CC[C@H](CN)C2)c2c(cnn2c1)C#N |r|

BDBM305787

CCOc1cc(-c2ccc(nc2)N2CC[C@H](CNC(=O)CC(C)C)C2)c2c(cnn2c1)C#N |r|

BDBM305788

CCOc1cc(-c2ccc(nc2)N2CC[C@H](CNC(=O)c3ncccc3Cl)C2)c2c(cnn2c1)C#N |r|

BDBM305350

CCOc1cc(-c2ccc(nc2)N2CC[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305501

CCOc1cc(-c2ccc(nc2)N2CC[C@H](N)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305509

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C(C)C(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305507

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(C)CCC3)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305508

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(CC3)C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305505

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(CCC3)C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305708

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3CC(F)(F)C3)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305703

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@@H](O)C2)c2c(Cl)cnn2c1 |r|

BDBM305502

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305710

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305503

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305709

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CCC(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305496

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)OC(C)(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305500

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)OC(C)(C)C)[C@H](C2)OCCN(C)C)c2c(cnn2c1)C#N |r|

BDBM305497

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)OC(C)(C)C)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305514

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)OC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305712

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(C)cccc3Cl)[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305705

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(F)cccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305713

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3C)[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305707

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305704

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305706

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305711

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3Cl)[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM305506

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305511

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3ncccc3Cl)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305702

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NCCC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305701

CCOc1cc(-c2ccc(nc2)N2CC[C@H](NS(=O)(=O)CC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305697

CCOc1cc(-c2ccc(nc2)N2CC[C@H](Oc3ccc(C)nn3)[C@@H](N)C2)c2c(cnn2c1)C#N |r|

BDBM296793

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(C)C3)c2c(cnn2c1)C#N |r|

BDBM296785

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(C3)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM296790

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(C3)C(C)=O)c2c(cnn2c1)C#N |r|

BDBM296797

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(C3)C(C)C)c2c(cnn2c1)C#N |r|

BDBM296792

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(C3)C2CC2)c2c(cnn2c1)C#N |r|

BDBM296826

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCN(CC)C3)c2c(cnn2c1)C#N |r|

BDBM296786

CCOc1cc(-c2ccc(nc2)N2CC[C@]3(C2)CCCNC3)c2c(cnn2c1)C#N |r|

BDBM305333

CCOc1cc(-c2ccc(nc2)N2C[C@@H](C[C@@H](C2)C(F)(F)F)NC)c2c(cnn2c1)C#N |r|

BDBM305489

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)NC(=O)CC(C)C)c2c(cnn2c1)C#N |r|

BDBM305339

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)OCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305341

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)OCCOC(C)C)c2c(cnn2c1)C#N |r|

BDBM305344

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)Oc2ccc(Cl)nn2)c2c(cnn2c1)C#N |r|

BDBM315706

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)Oc2ccc(OC)nc2)c2c(cnn2c1)C#N |r|

BDBM305342

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM315708

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@@H](C2)Oc2cnc(OC)c(F)c2)c2c(cnn2c1)C#N |r|

BDBM305338

CCOc1cc(-c2ccc(nc2)N2C[C@@H](N)[C@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305486

CCOc1cc(-c2ccc(nc2)N2C[C@@H](NC(=O)CC(C)C)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305487

CCOc1cc(-c2ccc(nc2)N2C[C@@H](NC(=O)c3ccccc3)[C@@H](C2)OC)c2c(cnn2c1)C#N |r|

BDBM305485

CCOc1cc(-c2ccc(nc2)N2C[C@@H](O)[C@H](C2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305360

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3N)c2c(cnn2c1)C#N |r|

BDBM305359

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305361

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H](C2)[C@@H]3Nc2nc(C)ccc2F)c2c(cnn2c1)C#N |r|

BDBM296771

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H]2CN3)c2c(cnn2c1)C#N |r|

BDBM296770

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H]2CN3C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM296331

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H]2CN3Cc2ccc(OC)nc2)c2c(cnn2c1)C#N |r|

BDBM296772

CCOc1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H]2CN3c2ccc(OC)nc2)c2c(cnn2c1)C#N |r|

BDBM296537

CCOc1cc(-c2ccc(nc2)N2C[C@H](C)N(Cc3ccc(OC)nc3)[C@H](C)C2)c2c(cnn2c1)C#N |r|

BDBM305332

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)C[C@@H](C2)C(F)(F)F)c2c(cnn2c1)C#N |r|

BDBM305351

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)C[C@H](C2)C(F)(F)F)c2c(cnn2c1)C#N |r|

BDBM305334

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305488

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)NC(=O)CC(C)C)c2c(cnn2c1)C#N |r|

BDBM305336

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)OCC(C)C)c2c(cnn2c1)C#N |r|

BDBM305337

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)OCCOC(C)C)c2c(cnn2c1)C#N |r|

BDBM305348

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2ccc(Cl)nn2)c2c(cnn2c1)C#N |r|

BDBM305408

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2ccc(OC)nc2)c2c(Cl)cnn2c1 |r|

BDBM315710

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2ccc(OC)nc2)c2c(cnn2c1)C#N |r|

BDBM305346

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305029

CCOc1cc(-c2ccc(nc2)N2C[C@H](N)[C@H](C2)Oc2cnc(OC)c(F)c2)c2c(cnn2c1)C#N |r|

BDBM305484

CCOc1cc(-c2ccc(nc2)N2C[C@H](O)[C@@H](C2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305483

CCOc1cc(-c2ccc(nc2)N2C[C@H](O)[C@H](C2)NC(=O)CC(C)C)c2c(cnn2c1)C#N |r|

BDBM303768

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2ccc(CC)nc2)c2c(cnn2c1)C#N

BDBM296812

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2ccc(OC)c(F)c2)c2c(cnn2c1)C#N

BDBM296813

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2ccc(OC)cn2)c2c(cnn2c1)C#N

BDBM296808

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c(cnn2c1)C#N

BDBM296824

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2cnc(OC)c(C)c2)c2c(cnn2c1)C#N

BDBM296810

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2cnc(OC)c(Cl)c2)c2c(cnn2c1)C#N

BDBM296809

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2cnc(OC)c(F)c2)c2c(cnn2c1)C#N

BDBM296825

CCOc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2cncc(F)c2)c2c(cnn2c1)C#N

BDBM305761

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2c(C)cccc2Cl)c2c(cnn2c1)C#N

BDBM305753

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2c(F)ccc(F)c2F)c2c(cnn2c1)C#N

BDBM305755

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305754

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2c(cnn2c1)C#N

BDBM305760

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2nc(C)ccc2C)c2c(cnn2c1)C#N

BDBM305759

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2nc(C)ccc2Cl)c2c(cnn2c1)C#N

BDBM305758

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2nc(C)ccc2F)c2c(cnn2c1)C#N

BDBM305757

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305756

CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM296807

CCOc1cc(-c2cnc(cn2)N2CCN(CC2)C(=O)[C@H](O)c2cccc(Cl)c2)c2c(cnn2c1)C#N |r|

BDBM305690

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)CC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305693

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3c(F)cccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM316054

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3cc(F)ccc3C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305692

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3ncccc3C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305694

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3ncccc3C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305689

CCOc1cc(-c2cnc(cn2)N2CC[C@H](NC(=O)c3ncccc3Cl)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305721

CCOc1cc(-c2ncc(cn2)N2CCC(CC2)Oc2ccc(OC)cn2)c2c(cnn2c1)C#N

BDBM296869

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2cc(OCCN(C)C)cc(c2)C(F)(F)F)c(F)c1

BDBM296868

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2cc(cc(c2)C(F)(F)F)C(=O)NCCN(C)C)c(F)c1

BDBM347339

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2cc(no2)C(C)(C)C(F)(F)F)c(F)c1

BDBM347342

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2cc(on2)C(C)(C)C(F)(F)F)c(F)c1

BDBM347350

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2ccc(C#N)c(c2)C(F)(F)F)c(F)c1

BDBM347319

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2ccc(C#N)c(c2)C(F)(F)F)cc1F

BDBM347313

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2ccc(CC(C)(C)CO)c(c2)C(F)(F)F)c(F)c1

BDBM347344

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2ccc(CC(C)(C)CO)c(c2)C(F)(F)F)cc1F

BDBM347332

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2ccc(OCCO)c(c2)C(F)(F)F)c(F)c1

BDBM347349

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2ccc(nc2)C(C)(C)C(F)(F)F)c(F)c1

BDBM347345

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2cccc(c2)C(F)(F)F)c(F)c1

BDBM347322

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2cnc(OCCN(C)C)c(c2)C(F)(F)F)c(F)c1

BDBM347343

CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2cnc(c(c2)C(F)(F)F)C(C)(C)CO)c(F)c1

BDBM376389

CCOc1cc(=O)ncc1-c1ccc(CC(=O)Nc2cc(OCCN(C)C)cc(c2)C(F)(F)F)c(F)c1

BDBM376119

CCOc1cc(=O)ncc1-c1ccc(CC(=O)Nc2cc(cc(c2)C(F)(F)F)C(=O)NCCN(C)C)c(F)c1

BDBM347320

CCOc1cc(c[nH]c1=O)-c1cc(F)c(CC(=O)Nc2ccc(OCCO)c(c2)C(F)(F)F)c(F)c1

BDBM347334

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(F)ccc2F)c(F)c1

BDBM347358

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(OCCN(C)C)cc(c2)C(F)(F)F)c(F)c1

BDBM347351

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(OCCN3CCOCC3)cc(c2)C(F)(F)F)c(F)c1

BDBM347336

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(c(F)cc2F)C(F)(F)F)c(F)c1

BDBM347348

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(cc(c2)C(F)(F)F)-c2cn[nH]c2)c(F)c1

BDBM347357

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(cc(c2)C(F)(F)F)-c2cnn(C)c2)c(F)c1

BDBM347356

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(cc(c2)C(F)(F)F)-c2nn[nH]n2)c(F)c1

BDBM347341

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(cc(c2)C(F)(F)F)-c2nnc(C)o2)c(F)c1

BDBM347346

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(cc(c2)C(F)(F)F)-n2cc(C)cn2)c(F)c1

BDBM347347

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(cc(c2)C(F)(F)F)-n2ccc(C)n2)c(F)c1

BDBM347323

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(cc(c2)C(F)(F)F)-n2cnc(C)c2)c(F)c1

BDBM347337

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(F)c1

BDBM347338

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(ccc2F)C(F)(F)F)c(F)c1

BDBM347354

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(n[nH]2)C(C)(C)C(F)(F)F)c(F)c1

BDBM347353

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(nn2C)C(C)(C)C(F)(F)F)c(F)c1

BDBM347340

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(no2)C(C)(C)C(F)(F)F)c(F)c1

BDBM347331

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cc(on2)C(C)(C)C(F)(F)F)c(F)c1

BDBM347321

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(C#N)c(c2)C(F)(F)F)c(F)c1

BDBM347335

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(C(N)=O)c(c2)C(F)(F)F)c(F)c1

BDBM347317

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(CC(C)(C)CO)c(c2)C(F)(F)F)c(F)c1

BDBM347318

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(CC(C)(C)CO)c(c2)C(F)(F)F)cc1F

BDBM347355

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(CC(F)(F)CO)c(c2)C(F)(F)F)c(F)c1

BDBM347329

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(CN(C)C)c(c2)C(F)(F)F)c(F)c1

BDBM347333

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(CN3CCN(CC)CC3)c(c2)C(F)(F)F)c(F)c1

BDBM50042943

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(Cl)c(Cl)c2)c(F)c1

BDBM347328

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c(F)c1

BDBM347325

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(OCCO)c(c2)C(F)(F)F)c(F)c1

BDBM347316

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2ccc(OCCO)c(c2)C(F)(F)F)c(F)c1F

BDBM347327

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cnc(C(C)C#N)c(c2)C(F)(F)F)c(F)c1

BDBM347326

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cnc(CC#N)c(c2)C(F)(F)F)c(F)c1

BDBM347311

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cnc(OCC)c(c2)C(F)(F)F)c(F)c1

BDBM347324

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cnc(c(c2)C(F)(F)F)C(C)(C)C#N)c(F)c1

BDBM347310

CCOc1cc(c[nH]c1=O)-c1ccc(CC(=O)Nc2cnc(c(c2)C(F)(F)F)C(C)(C)O)c(F)c1

BDBM284633

CCOc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM296234

CCOc1cn2ncc(C#N)c2c(n1)-c1ccc(nc1)N1CCN(CC1)C(=O)NCC(C)C

BDBM296603

CCOc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1F

BDBM296766

CCOc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(Cl)c23)cc1F

BDBM284112

CC[C@@H](CO)NC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM296404

CC[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM296403

CC[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](OC)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296406

CC[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(Cl)cn3)CC2)c2c(cnn2c1)C#N |r|

BDBM296407

CC[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)cn3)CC2)c2c(cnn2c1)C#N |r|

BDBM296408

CC[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N |r|

BDBM296405

CC[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N |r|

BDBM284086

CC[C@H](CO)NC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284140

CC[C@H](O)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM296411

CC[C@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N |r|

BDBM296409

CC[C@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296410

CC[C@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](OC)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296413

CC[C@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(Cl)cn3)CC2)c2c(cnn2c1)C#N |r|

BDBM296414

CC[C@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)cn3)CC2)c2c(cnn2c1)C#N |r|

BDBM296415

CC[C@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N |r|

BDBM296412

CC[C@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N |r|

BDBM296546

CCc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305253

CCc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM296671

CCc1ccc(cn1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305066

CCc1cccc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305059

CCc1ccccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284624

CCc1cnn2cc(cc(-c3ccc(nc3)N3CCN(CC3)C(=O)N3CC[C@@H](C3)OC)c12)-c1cnn(C)c1 |r|

BDBM284623

CCc1cnn2cc(cc(-c3ccc(nc3)N3CCN(CC3)C(=O)[C@H](O)c3ccccc3)c12)-c1cnn(C)c1 |r|

BDBM284622

CCc1cnn2cc(cc(-c3ccc(nc3)N3CCNCC3)c12)-c1cnn(C)c1

BDBM296580

CCc1csc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1

BDBM284582

CCc1nn(C)cc1-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284587

CCc1nn(CC)cc1-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM296606

CCn1cc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)ccc1=O

BDBM296575

CCn1cc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM284436

CCn1cc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM284581

CCn1cc(c(C)n1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284099

CN(C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1

BDBM284313

CN(C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2nccc12)-c1cnn(C)c1)c1ccccc1

BDBM284547

CN(C)C(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284136

CN(C)C(=O)CCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284133

CN(C)C(=O)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305391

CN(C)C(=O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM284488

CN(C)C(=O)N1CC2(C1)CCN(CC2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284122

CN(C)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284176

CN(C)C(=O)NC1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305645

CN(C)C(=O)Oc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM305646

CN(C)C(=O)Oc1cc(-c2ccc(nc2)N2CCC(C)(N)CC2)c2c(cnn2c1)C#N

BDBM296676

CN(C)C(C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12)c1ccc(F)cc1

BDBM296544

CN(C)C(C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12)c1ccc(F)cc1

BDBM284341

CN(C)C(C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccc(F)cc1

BDBM284481

CN(C)CC(=O)N1CC2(C1)CCN(CC2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284326

CN(C)CC(=O)N1CC2CCC(C1)N2c1ccc(cn1)-c1cc(cn2ncc(Cl)c12)-c1cnn(C)c1

BDBM284293

CN(C)CC(=O)N1CCC(CC1)c1ccc(cc1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284286

CN(C)CC(=O)N1CCN(CC1)c1ccc(cc1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284318

CN(C)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(Cl)c12)-c1cnn(C)c1

BDBM284023

CN(C)CCC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284042

CN(C)CCCC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296594

CN(C)CCCOc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1

BDBM284471

CN(C)CCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305288

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305428

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N

BDBM305444

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM305419

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305299

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305383

CN(C)CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM296215

CN(C)CCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305668

CN(C)CCOc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2c(C)cccc2Cl)c2c(cnn2c1)C#N

BDBM305126

CN(C)Cc1cccc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284317

CN(C)[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(Cl)c12)-c1cnn(C)c1 |r|

BDBM284626

CN(C)[C@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1 |r|

BDBM296556

CN(C)c1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM284451

CN(C)c1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cc1

BDBM284630

CN(C)c1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM284450

CN(C)c1ccccc1CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296565

CN(C)c1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)s1

BDBM284376

CN(C1CC1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305292

CN1CC(C)(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3cc(F)ccc3C)c3c(cnn3c2)C#N)C1

BDBM296208

CN1CC(C1)Oc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305385

CN1CC(CCOc2cc(-c3ccc(nc3)N3CCC(CC3)Oc3ccccn3)c3c(cnn3c2)C#N)C1

BDBM296212

CN1CC(CCOc2cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c3c(cnn3c2)C#N)C1

BDBM305443

CN1CC(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccn3)c3c(cnn3c2)C#N)C1

BDBM296210

CN1CC(COc2cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c3c(cnn3c2)C#N)C1

BDBM305287

CN1CC(F)(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3cc(F)ccc3C)c3c(cnn3c2)C#N)C1

BDBM305424

CN1CC(F)(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccc3)c3c(cnn3c2)C#N)C1

BDBM305446

CN1CC(F)(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccn3)c3c(cnn3c2)C#N)C1

BDBM305300

CN1CC(F)(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ncccc3Cl)c3c(cnn3c2)C#N)C1

BDBM284132

CN1CCC(N2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)C1=O

BDBM284541

CN1CCC2(CCCN(C2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)CC1

BDBM284540

CN1CCC2(CN(C2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)CC1

BDBM284543

CN1CCCC11CCCN(C1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284542

CN1CCCC2(CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)C1

BDBM284351

CN1CCN(CC(=O)N2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)CC1

BDBM284110

CN1CCN(CC1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284323

CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(Cl)c12)-c1cnn(C)c1

BDBM305294

CN1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3cc(F)ccc3C)c3c(cnn3c2)C#N)CC1

BDBM305425

CN1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccc3)c3c(cnn3c2)C#N)CC1

BDBM305448

CN1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccn3)c3c(cnn3c2)C#N)CC1

BDBM305382

CN1CCN(CCOc2cc(-c3ccc(nc3)N3CCC(CC3)Oc3ccccn3)c3c(cnn3c2)C#N)CC1

BDBM296359

CN1CCN(CCOc2cc(-c3ccc(nc3)N3CCN(CC3)C(=O)[C@H](O)c3ccccc3)c3c(cnn3c2)C#N)CC1 |r|

BDBM296214

CN1CCN(CCOc2cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c3c(cnn3c2)C#N)CC1

BDBM305386

CN1CCOC(COc2cc(-c3ccc(nc3)N3CCC(CC3)Oc3ccccn3)c3c(cnn3c2)C#N)C1

BDBM305661

CN1CCO[C@@H](COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ncccc3Cl)c3c(cnn3c2)C#N)C1 |r|

BDBM305660

CN1CCO[C@H](COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ncccc3Cl)c3c(cnn3c2)C#N)C1 |r|

BDBM305094

CN1CCc2c(C1)cccc2C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296729

CNC(=O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c(cnn2c1)C#N

BDBM305390

CNC(=O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM284377

CNC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284470

CNCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284289

CNS(=O)(=O)N1CCN(CC1)c1ccc(cc1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284244

COC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284288

COC(=O)N1CCN(CC1)c1ccc(cc1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284404

COC(C)(C)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296695

COC(C)(C)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3S(=O)(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM296694

COC(C)(C)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3S(=O)(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM296511

COC(C)(C)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM296800

COC(C)(C)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2cccc(Cl)c2)c2c(cnn2c1)C#N |r|

BDBM296512

COC(C)(C)COc1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM284229

COC(C)CNC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284674

COC(C)Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM284407

COC(CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)C(C)(C)C

BDBM284403

COC(CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)C(C)C

BDBM284226

COC(CNC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)C(C)C

BDBM284225

COC(CNC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)C(F)(F)F

BDBM296652

COC1CCC(CC1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |(12,-1.6,;10.67,-.83,;9.34,-1.6,;9.34,-3.14,;8,-3.91,;6.67,-3.14,;6.67,-1.6,;8,-.83,;5.33,-3.91,;5.33,-5.45,;4,-3.14,;2.67,-3.91,;2.67,-2.37,;4,-1.6,;2.67,-.83,;1.33,-1.6,;1.33,-3.14,;,-.83,;-1.33,-1.6,;-2.67,-.83,;-2.67,.71,;-1.33,1.48,;,.71,;-4,1.48,;-5.33,.71,;-6.67,1.48,;-8,.71,;-9.34,1.48,;-10.67,.71,;-11.44,-.63,;-9.9,-.63,;-12,1.48,;-6.67,3.02,;-5.33,3.79,;-5.01,5.29,;-3.48,5.45,;-2.86,4.05,;-1.37,3.65,;.12,3.25,;-4,3.02,)|

BDBM284366

COC1CCN(CC1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305260

COC1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284188

COC1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284282

COCC(=O)N1CCN(CC1)c1ccc(cc1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284030

COCC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284319

COCC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(Cl)c12)-c1cnn(C)c1

BDBM284173

COCC(=O)NC1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284342

COCC(C)(C)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284242

COCC(C)NC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284222

COCC(C)NC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284343

COCC1(CC1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284344

COCC1(CCC1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284395

COCCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296202

COCCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284120

COCCN(C)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284375

COCCN(CCOC)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296720

COCCN1CC(C)(COc2cc(-c3ccc(nc3)N3CC4CC(C3)N4Cc3ccc(OC)nc3)c3c(cnn3c2)C#N)C1

BDBM284680

COCCN1CCC(CC1)n1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)C(C)C)c2c(cnn2c1)C#N |r|

BDBM296710

COCCN1CCC(CCOc2cc(-c3ccc(nc3)N3CC4CC(C3)N4Cc3ccc(OC)nc3)c3c(cnn3c2)C#N)CC1

BDBM296708

COCCN1CCC(COc2cc(-c3ccc(nc3)N3CC4CC(C3)N4Cc3ccc(OC)nc3)c3c(cnn3c2)C#N)CC1

BDBM284386

COCCN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284125

COCCNC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305142

COCCOC1CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305397

COCCOc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM296696

COCCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c(cnn2c1)C#N

BDBM305418

COCCOc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM296470

COCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CC(C)C)c2c(cnn2c1)C#N

BDBM296474

COCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM296468

COCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM430472

COCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM296472

COCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)C(C)C)c2c(cnn2c1)C#N |r|

BDBM296471

COCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296473

COCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](OC)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296478

COCCOc1cc(-c2ccc(nc2)N2CCN(CC3CCOCC3)CC2)c2c(cnn2c1)C#N

BDBM296475

COCCOc1cc(-c2ccc(nc2)N2CCN(CCOC(C)C)CC2)c2c(cnn2c1)C#N

BDBM303452

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3cc(C)nc(C)c3)CC2)c2c(cnn2c1)C#N

BDBM296489

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3cc(OC)ccn3)CC2)c2c(cnn2c1)C#N

BDBM296488

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(C)cn3)CC2)c2c(cnn2c1)C#N

BDBM296485

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(C)nc3)CC2)c2c(cnn2c1)C#N

BDBM296483

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(Cl)cn3)CC2)c2c(cnn2c1)C#N

BDBM296484

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(Cl)nc3)CC2)c2c(cnn2c1)C#N

BDBM296482

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(F)cn3)CC2)c2c(cnn2c1)C#N

BDBM296487

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)cn3)CC2)c2c(cnn2c1)C#N

BDBM296476

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM296493

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3cccc(C)n3)CC2)c2c(cnn2c1)C#N

BDBM296479

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3cccc(OC)n3)CC2)c2c(cnn2c1)C#N

BDBM296205

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM296480

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM296481

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3cccnc3)CC2)c2c(cnn2c1)C#N

BDBM296486

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccnc(C)c3)CC2)c2c(cnn2c1)C#N

BDBM296494

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3cncc(C)c3)CC2)c2c(cnn2c1)C#N

BDBM296492

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3cncc(Cl)c3)CC2)c2c(cnn2c1)C#N

BDBM296491

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3cncc(F)c3)CC2)c2c(cnn2c1)C#N

BDBM296490

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3cncc(OC)c3)CC2)c2c(cnn2c1)C#N

BDBM296477

COCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ncccn3)CC2)c2c(cnn2c1)C#N

BDBM296469

COCCOc1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM284700

COCCn1cc(nn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)NCC(C)C)c2c(cnn2c1)C#N

BDBM284699

COCCn1cc(nn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)C(C)C)c2c(cnn2c1)C#N |r|

BDBM284698

COCCn1cc(nn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N

BDBM284356

COCCn1ccc(n1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284101

COC[C@@H]1CCCN1C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284141

COC[C@H](O)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284100

COC[C@H]1CCCN1C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM305084

COCc1cccc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284549

CONC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM303423

CO[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OC2COC[C@@H]2O)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM296422

CO[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM296513

CO[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)OC)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM296451

CO[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCCO)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM296366

CO[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM296387

CO[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OC[C@@H](C)O)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM296396

CO[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OC[C@H](C)O)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM296417

CO[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(O[C@@H](C)[C@@H](C)O)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM430468

CO[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(O[C@H]2COC[C@@H]2O)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM284685

CO[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnc(C)o1)c1ccccc1 |r|

BDBM284073

CO[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1 |r|

BDBM284274

CO[C@@H](C(=O)N1CCN(CC1)c1ncc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1 |r|

BDBM284405

CO[C@@H](C)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM296508

CO[C@@H](C)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](OC)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296509

CO[C@@H](C)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N |r|

BDBM296510

CO[C@@H](C)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N |r|

BDBM284094

CO[C@@H]1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM305473

CO[C@@H]1CN(CC[C@H]1NC(=O)OC(C)(C)C)c1ccc(cn1)-c1cc(OC)cn2ncc(C#N)c12 |r|

BDBM284406

CO[C@@H]1COCC1N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284190

CO[C@@H]1C[C@@H]2CC[C@H](C1)N2c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r,THB:10:9:8.2.3:5.6|

BDBM284362

CO[C@@](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)(c1ccccc1)C(F)(F)F |r|

BDBM296454

CO[C@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCCO)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM296369

CO[C@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM284684

CO[C@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnc(C)o1)c1ccccc1 |r|

BDBM284074

CO[C@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1 |r|

BDBM284076

CO[C@H](C(C)C)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284402

CO[C@H](C)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM296501

CO[C@H](C)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM296503

CO[C@H](C)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](OC)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296507

CO[C@H](C)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(C)cn3)CC2)c2c(cnn2c1)C#N |r|

BDBM296505

CO[C@H](C)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(Cl)cn3)CC2)c2c(cnn2c1)C#N |r|

BDBM296506

CO[C@H](C)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)cn3)CC2)c2c(cnn2c1)C#N |r|

BDBM296504

CO[C@H](C)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC)nc3)CC2)c2c(cnn2c1)C#N |r|

BDBM296502

CO[C@H](C)COc1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N |r|

BDBM284230

CO[C@H]1CC(C1)NC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r,wD:2.1,(10.8,-6,;9.46,-6.77,;8.13,-6,;7.73,-4.51,;6.24,-4.91,;6.64,-6.4,;4.91,-4.14,;4.91,-2.6,;6.24,-1.83,;3.58,-1.83,;2.24,-2.6,;.91,-1.83,;.91,-.29,;2.24,.48,;3.58,-.29,;-.43,.48,;-.43,2.02,;-1.76,2.79,;-3.09,2.02,;-3.09,.48,;-1.76,-.29,;-4.43,2.79,;-5.76,2.02,;-7.09,2.79,;-7.09,4.33,;-5.76,5.1,;-5.44,6.61,;-3.91,6.77,;-3.28,5.36,;-1.79,4.96,;-.31,4.56,;-4.43,4.33,;-8.43,2.02,;-9.89,2.5,;-10.8,1.25,;-9.89,0,;-10.66,-1.33,;-8.43,.48,)|

BDBM284231

CO[C@H]1CC(C1)NC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r,wU:2.1,(10.8,-6,;9.46,-6.77,;8.13,-6,;6.64,-6.4,;6.24,-4.91,;7.73,-4.51,;4.91,-4.14,;4.91,-2.6,;6.24,-1.83,;3.58,-1.83,;2.24,-2.6,;.91,-1.83,;.91,-.29,;2.24,.48,;3.58,-.29,;-.43,.48,;-.43,2.02,;-1.76,2.79,;-3.09,2.02,;-3.09,.48,;-1.76,-.29,;-4.43,2.79,;-5.76,2.02,;-7.09,2.79,;-7.09,4.33,;-5.76,5.1,;-5.44,6.61,;-3.91,6.77,;-3.28,5.36,;-1.79,4.96,;-.31,4.56,;-4.43,4.33,;-8.43,2.02,;-9.89,2.5,;-10.8,1.25,;-9.89,0,;-10.66,-1.33,;-8.43,.48,)|

BDBM296684

CO[C@H]1CCN(C1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM296218

CO[C@H]1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OC)cn2ncc(C#N)c12 |r|

BDBM284264

CO[C@H]1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1ccn(C)n1 |r|

BDBM284580

CO[C@H]1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cn(C)nc1C |r|

BDBM284087

CO[C@H]1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284578

CO[C@H]1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1C |r|

BDBM284259

CO[C@H]1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(c1)C(F)F |r|

BDBM284612

CO[C@H]1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(Cl)c12)-c1cnn(C)c1 |r|

BDBM284611

CO[C@H]1CCN(C1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2nccc12)-c1cnn(C)c1 |r|

BDBM284279

CO[C@H]1CCN(C1)C(=O)N1CCN(CC1)c1cnc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284276

CO[C@H]1CCN(C1)C(=O)N1CCN(CC1)c1ncc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM296661

CO[C@H]1C[C@@H](C1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r,wU:4.6,wD:2.1,(10.95,.26,;10.95,-1.28,;9.61,-2.05,;8.12,-1.66,;7.73,-3.14,;9.21,-3.54,;6.39,-3.91,;6.39,-5.45,;5.06,-3.14,;3.72,-3.91,;3.72,-2.37,;5.06,-1.6,;3.72,-.83,;2.39,-1.6,;2.39,-3.14,;1.06,-.83,;-.28,-1.6,;-1.61,-.83,;-1.61,.71,;-.28,1.48,;1.06,.71,;-2.94,1.48,;-4.28,.71,;-5.61,1.48,;-6.94,.71,;-8.28,1.48,;-9.61,.71,;-10.38,-.63,;-8.84,-.63,;-10.95,1.48,;-5.61,3.02,;-4.28,3.79,;-3.96,5.29,;-2.43,5.45,;-1.8,4.05,;-.31,3.65,;1.18,3.25,;-2.94,3.02,)|

BDBM296664

CO[C@H]1C[C@H](C1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r,wU:4.6,2.1,(10.95,.26,;10.95,-1.28,;9.61,-2.05,;9.21,-3.54,;7.73,-3.14,;8.12,-1.66,;6.39,-3.91,;6.39,-5.45,;5.06,-3.14,;3.72,-3.91,;3.72,-2.37,;5.06,-1.6,;3.72,-.83,;2.39,-1.6,;2.39,-3.14,;1.06,-.83,;-.28,-1.6,;-1.61,-.83,;-1.61,.71,;-.28,1.48,;1.06,.71,;-2.94,1.48,;-4.28,.71,;-5.61,1.48,;-6.94,.71,;-8.28,1.48,;-9.61,.71,;-10.38,-.63,;-8.84,-.63,;-10.95,1.48,;-5.61,3.02,;-4.28,3.79,;-3.96,5.29,;-2.43,5.45,;-1.8,4.05,;-.31,3.65,;1.18,3.25,;-2.94,3.02,)|

BDBM284361

CO[C@](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)(c1ccccc1)C(F)(F)F |r|

BDBM296581

COc1c(F)cc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1F

BDBM305092

COc1c(F)cc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296823

COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c(CC#N)cnn2c1

BDBM296822

COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c(cnn2c1)C(C)C#N

BDBM305297

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)N(C)C(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305482

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC(C)C)c2c(Cl)cnn2c1

BDBM305480

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC(C)C)c2c(cnn2c1)C#N

BDBM305405

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c(F)cccc2Cl)c2c(Cl)cnn2c1

BDBM305402

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2c(F)cccc2Cl)c2ccnn2c1

BDBM305285

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C)c2c(cnn2c1)C#N

BDBM305406

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2c(Cl)cnn2c1

BDBM305403

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2ccnn2c1

BDBM305417

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305404

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(Cl)cnn2c1

BDBM305296

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305407

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C1CC1

BDBM305401

COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2ccnn2c1

BDBM305400

COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(C)nn2)c2c(Cl)cnn2c1

BDBM305481

COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(Cl)cnn2c1

BDBM305472

COc1cc(-c2ccc(nc2)N2CCC(CC2)S(=O)(=O)NC(C)C)c2c(cnn2c1)C#N

BDBM296216

COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(CO)c2ccccc2)c2c(cnn2c1)C#N

BDBM296217

COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2ccc(F)cn2)c2c(cnn2c1)C#N

BDBM296195

COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM305479

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C(C)C(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305477

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(C)CCC3)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305478

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(CC3)C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305476

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)C3(CCC3)C(F)(F)F)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305475

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)CC(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305474

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)OC(C)(C)C)[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305700

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3c(F)cccc3Cl)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM305699

COc1cc(-c2ccc(nc2)N2CC[C@H](NC(=O)c3cc(F)ccc3Cl)[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM296821

COc1cc(-c2cnc(cn2)N2CC3CC(C2)N3Cc2ccc(OC)nc2)c2c(Cl)cnn2c1

BDBM305775

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2c(F)ccc(F)c2F)c2c(cnn2c1)C#N

BDBM305777

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2C(F)(F)F)c2c(cnn2c1)C#N

BDBM305776

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2cc(F)ccc2Cl)c2c(cnn2c1)C#N

BDBM305778

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2nc(C)ccc2Cl)c2c(cnn2c1)C#N

BDBM305774

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncc(F)cc2Cl)c2c(cnn2c1)C#N

BDBM305746

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(Cl)cnn2c1

BDBM305773

COc1cc(-c2cnc(cn2)N2CCC(C)(CC2)NC(=O)c2ncccc2Cl)c2c(cnn2c1)C#N

BDBM305752

COc1cc(-c2cnc(cn2)N2CCC(Cc3ccccc3)(CC2)NC(=O)[C@H](O)CO)c2c(cnn2c1)C#N |r|

BDBM305748

COc1cc(-c2cnc(cn2)N2CCC(O)(Cc3ncccc3F)CC2)c2c(cnn2c1)C#N

BDBM296557

COc1cc(C)c(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM284637

COc1cc(C)c(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM296605

COc1cc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cnc1OC

BDBM284390

COc1cc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)ccn1

BDBM284635

COc1cc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cnc1OC

BDBM305119

COc1cc(OC)nc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305114

COc1ccc(C)c(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305723

COc1ccc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM303406

COc1ccc(CN2C3CC2CN(C3)c2ccc(cc2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM315816

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC3CC(O)C3)cn3ncc(C#N)c23)cn1 |(12.28,-2.37,;10.95,-1.6,;9.61,-2.37,;8.28,-1.6,;6.94,-2.37,;6.94,-3.91,;5.61,-4.68,;4.28,-3.91,;2.94,-4.68,;2.94,-3.14,;4.28,-2.37,;2.94,-1.6,;1.61,-2.37,;1.61,-3.91,;.28,-1.6,;-1.06,-2.37,;-2.39,-1.6,;-2.39,-.06,;-1.06,.71,;.28,-.06,;-3.72,.71,;-5.06,-.06,;-6.39,.71,;-7.73,-.06,;-9.06,.71,;-10.55,.31,;-10.95,1.8,;-12.28,2.57,;-9.46,2.19,;-6.39,2.25,;-5.06,3.02,;-4.74,4.52,;-3.21,4.68,;-2.58,3.28,;-1.09,2.88,;.39,2.48,;-3.72,2.25,;8.28,-4.68,;9.61,-3.91,)|

BDBM296706

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC3CCN(C)CC3)cn3ncc(C#N)c23)cn1

BDBM296724

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC3C[C@H](O)C3)cn3ncc(C#N)c23)cn1 |r,wU:26.29,(12.54,-2.37,;11.21,-1.6,;9.87,-2.37,;8.54,-1.6,;7.21,-2.37,;7.21,-3.91,;5.87,-4.68,;4.54,-3.91,;3.21,-4.68,;3.21,-3.14,;4.54,-2.37,;3.21,-1.6,;1.87,-2.37,;1.87,-3.91,;.54,-1.6,;-.8,-2.37,;-2.13,-1.6,;-2.13,-.06,;-.8,.71,;.54,-.06,;-3.46,.71,;-4.8,-.06,;-6.13,.71,;-7.46,-.06,;-8.95,.33,;-9.72,1.67,;-11.05,.9,;-12.54,1.3,;-10.28,-.44,;-6.13,2.25,;-4.8,3.02,;-4.48,4.52,;-2.94,4.68,;-2.32,3.28,;-.83,2.88,;.66,2.48,;-3.46,2.25,;8.54,-4.68,;9.87,-3.91,)|

BDBM296730

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(=O)N(C)C)cn3ncc(C#N)c23)cn1

BDBM296592

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c(C)c1

BDBM296585

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c(C)n1

BDBM296604

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c(OC)n1

BDBM296547

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1

BDBM296590

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1Cl

BDBM296593

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1Cn1cccn1

BDBM296589

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1F

BDBM296429

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM303389

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM296564

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1

BDBM296763

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(Cl)c23)cn1

BDBM296728

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(N)=O)cn3ncc(C#N)c23)cn1

BDBM296719

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3(C)CN(C)C3)cn3ncc(C#N)c23)cn1

BDBM296721

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3(C)CN(C3)C(C)=O)cn3ncc(C#N)c23)cn1

BDBM296718

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3(C)CNC3)cn3ncc(C#N)c23)cn1

BDBM296722

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3(C)COC3)cn3ncc(C#N)c23)cn1

BDBM296717

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3(F)CN(C)C3)cn3ncc(C#N)c23)cn1

BDBM296716

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3(F)CNC3)cn3ncc(C#N)c23)cn1

BDBM296749

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3(O)CC3)cn3ncc(C#N)c23)cn1

BDBM296707

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3CCN(C)CC3)cn3ncc(C#N)c23)cn1

BDBM296714

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3CN(C)C3)cn3ncc(C#N)c23)cn1

BDBM296715

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3CN(C3)C(C)=O)cn3ncc(C#N)c23)cn1

BDBM296713

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC3CNC3)cn3ncc(C#N)c23)cn1

BDBM296709

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCC3CCN(C)CC3)cn3ncc(C#N)c23)cn1

BDBM296727

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCC3CN(C)C3)cn3ncc(C#N)c23)cn1

BDBM296726

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCC3CNC3)cn3ncc(C#N)c23)cn1

BDBM296697

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCN(C)C)cn3ncc(C#N)c23)cn1

BDBM296711

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCN3CCCC3)cn3ncc(C#N)c23)cn1

BDBM296712

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCN3CCCC3=O)cn3ncc(C#N)c23)cn1

BDBM296705

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCN3CCNC(=O)C3)cn3ncc(C#N)c23)cn1

BDBM296704

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCN3CCOCC3)cn3ncc(C#N)c23)cn1

BDBM296376

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCO)cn3ncc(C#N)c23)cn1

BDBM315457

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCO)cn3ncc(C#N)c23)nc1

BDBM296735

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCn3ccnc3)cn3ncc(C#N)c23)cn1

BDBM296394

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@@H](C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM315476

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@@H](C)O)cn3ncc(C#N)c23)nc1 |r|

BDBM296699

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@@H]3CN(C)CCO3)cn3ncc(C#N)c23)cn1 |r|

BDBM296700

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@@H]3CNC(C)(C)CO3)cn3ncc(C#N)c23)cn1 |r|

BDBM296698

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@@H]3CNCCO3)cn3ncc(C#N)c23)cn1 |r|

BDBM296725

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@@H]3C[C@H](O)C3)cn3ncc(C#N)c23)cn1 |r,wU:25.27,27.30,(12.95,-2.37,;11.61,-1.6,;10.28,-2.37,;8.94,-1.6,;7.61,-2.37,;7.61,-3.91,;6.28,-4.68,;4.94,-3.91,;3.61,-4.68,;3.61,-3.14,;4.94,-2.37,;3.61,-1.6,;2.28,-2.37,;2.28,-3.91,;.94,-1.6,;-.39,-2.37,;-1.72,-1.6,;-1.72,-.06,;-.39,.71,;.94,-.06,;-3.06,.71,;-4.39,-.06,;-5.72,.71,;-7.06,-.06,;-8.39,.71,;-9.73,-.06,;-11.21,.34,;-11.61,-1.15,;-12.95,-1.92,;-10.12,-1.55,;-5.72,2.25,;-4.39,3.02,;-4.07,4.52,;-2.54,4.68,;-1.91,3.28,;-.43,2.88,;1.06,2.48,;-3.06,2.25,;8.94,-4.68,;10.28,-3.91,)|

BDBM296402

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@H](C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM296738

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@H](O)C(F)(F)F)cn3ncc(C#N)c23)cn1 |r|

BDBM296748

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@H](O)CN(C)C)cn3ncc(C#N)c23)cn1 |r|

BDBM296747

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@H](O)CO)cn3ncc(C#N)c23)cn1 |r|

BDBM296736

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCc3cccnc3)cn3ncc(C#N)c23)cn1

BDBM296732

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCc3cn(C)cn3)cn3ncc(C#N)c23)cn1

BDBM296731

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCc3cncn3C)cn3ncc(C#N)c23)cn1

BDBM296734

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCc3nc(C)co3)cn3ncc(C#N)c23)cn1

BDBM296737

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCc3nccn3C)cn3ncc(C#N)c23)cn1

BDBM296733

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCc3ncco3)cn3ncc(C#N)c23)cn1

BDBM284657

COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM296450

COc1ccc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296818

COc1ccc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OCC3(F)CNC3)cn3ncc(C#N)c23)cn1

BDBM296815

COc1ccc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OCCN3CCOCC3)cn3ncc(C#N)c23)cn1

BDBM296816

COc1ccc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OC[C@@H]3CNCCO3)cn3ncc(C#N)c23)cn1 |r|

BDBM296817

COc1ccc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OC[C@H]3CNCCO3)cn3ncc(C#N)c23)cn1 |r|

BDBM296757

COc1ccc(CN2C3CC2CN(C3)c2ncc(cc2C)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296756

COc1ccc(CN2C3CC2CN(C3)c2ncc(cc2F)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296762

COc1ccc(CN2C3CC2CN(C3)c2ncc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296820

COc1ccc(CN2C3CC2CN(C3)c2ncc(cn2)-c2cc(OCCN3CCOCC3)cn3ncc(C#N)c23)cn1

BDBM296444

COc1ccc(CN2C3CCC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296754

COc1ccc(CN2C3COCC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296768

COc1ccc(CN2CC3(C2)CCN(CC3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296448

COc1ccc(CN2CC3CC(C2)N3c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296445

COc1ccc(CN2CC3CCC(C2)N3c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296804

COc1ccc(CN2CCCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM284650

COc1ccc(CN2CCN(C(=O)C2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM284705

COc1ccc(CN2CCN(CC2)c2ccc(cc2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM296221

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OC(F)F)cn3ncc(C#N)c23)cn1

BDBM296344

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)C)cn3ncc(C#N)c23)cn1

BDBM296424

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296427

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM303300

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)C)cn3ncc(C#N)c23)cn1

BDBM296465

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCC3(CO)COC3)cn3ncc(C#N)c23)cn1

BDBM296351

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCC3CCC3)cn3ncc(C#N)c23)cn1

BDBM296461

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCCCO)cn3ncc(C#N)c23)cn1

BDBM296459

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCCCO)cn3ncc(C#N)c23)nc1

BDBM296374

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCCO)cn3ncc(C#N)c23)nc1

BDBM296498

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCCOC(C)C)cn3ncc(C#N)c23)cn1

BDBM296389

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OC[C@@H](C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM296392

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OC[C@@H](C)O)cn3ncc(C#N)c23)nc1 |r|

BDBM296462

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OC[C@@H](O)CO)cn3ncc(C#N)c23)cn1 |r|

BDBM296467

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OC[C@@H]3CN[C@H](C)CO3)cn3ncc(C#N)c23)cn1 |r|

BDBM296401

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OC[C@H](C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM296399

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OC[C@H](C)O)cn3ncc(C#N)c23)nc1 |r|

BDBM296464

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OC[C@H](O)CO)cn3ncc(C#N)c23)cn1 |r|

BDBM296364

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCc3cccnc3)cn3ncc(C#N)c23)cn1

BDBM296362

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCc3nc(C)no3)cn3ncc(C#N)c23)cn1

BDBM430364

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(OCc3nc(C)no3)cn3ncc(C#N)c23)nc1

BDBM284607

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cc(C)n(C)n2)cn1

BDBM284681

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cc(C)n(C[C@@H](C)CO)n2)cn1 |r|

BDBM284606

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cc(C)n[nH]2)cn1

BDBM284605

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cc(C)no2)cn1

BDBM284695

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cn(nn2)C(C)C)cn1

BDBM284663

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cn[nH]c2)cn1

BDBM284686

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnc(C)o2)cn1

BDBM284689

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnc(C)s2)cn1

BDBM284643

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)c(C)n1

BDBM284636

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)c(OC)n1

BDBM284422

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cc1

BDBM284464

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM284448

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)nc1

BDBM284675

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(CC(=O)N(C)C)c2)cn1

BDBM284667

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(CC(C)(C)O)c2)cn1

BDBM284671

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(CCC(=O)N(C)C)c2)cn1

BDBM284669

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(CCOC(C)C)c2)cn1

BDBM284668

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(CCS(=O)(=O)C(C)C)c2)cn1

BDBM284673

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C[C@@H](C)CO)c2)cn1 |r|

BDBM284665

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C[C@@H](C)O)c2)cn1 |r|

BDBM284672

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C[C@H](C)CO)c2)cn1 |r|

BDBM284666

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C[C@H](C)O)c2)cn1 |r|

BDBM284662

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(c2)C(C)C)cn1

BDBM284661

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(c2)C(F)F)cn1

BDBM284679

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(c2)C2CCN(C)CC2)cn1

BDBM284677

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(c2)C2CCN(CC2)C(=O)OC(C)(C)C)cn1

BDBM284678

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(c2)C2CCNCC2)cn1

BDBM284670

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(c2)C2CCOCC2)cn1

BDBM284676

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(c2)C2CNC2)cn1

BDBM284690

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2sc(C)nc2C)cn1

BDBM284709

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C)c23)-c2cnn(C)c2)cn1

BDBM284707

COc1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(Cl)c23)-c2cnn(C)c2)cn1

BDBM284701

COc1ccc(CN2CCN(CC2)c2ncc(cc2F)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM296753

COc1ccc(CN2CCN(CC22CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296752

COc1ccc(CN2CCN([C@H](C)C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM315844

COc1ccc(CN2CCN([C@H](C)C2=O)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM296447

COc1ccc(CN2C[C@@H]3C[C@H]2CN3c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM296446

COc1ccc(CN2C[C@H]3C[C@@H]2CN3c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM284570

COc1ccc(Cn2cc(cn2)-c2cc(-c3ccc(nc3)N3CCNCC3)c3c(cnn3c2)C#N)cc1

BDBM305091

COc1ccc(F)c(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305090

COc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305018

COc1ccc(NC(=O)C2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296687

COc1ccc(NC(=O)N2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1

BDBM296686

COc1ccc(NC(=O)N2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296767

COc1ccc(NC(=O)N2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(Cl)c23)cn1

BDBM305026

COc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305236

COc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM305031

COc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1

BDBM305414

COc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(Cl)c23)cn1

BDBM305161

COc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305151

COc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM305163

COc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1

BDBM305189

COc1ccc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM305196

COc1ccc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1 |r|

BDBM284334

COc1ccc(cc1)C1(CC1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284373

COc1ccc(cc1)N(C)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296635

COc1ccc(cc1Cl)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284655

COc1ccc(cc1Cl)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296636

COc1ccc(cc1F)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284654

COc1ccc(cc1F)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296761

COc1ccc(cn1)C(=O)N1C2CC1CN(C2)c1ccc(cc1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296518

COc1ccc(cn1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296723

COc1ccc(cn1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC2(C)COC2)cn2ncc(C#N)c12

BDBM296701

COc1ccc(cn1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM296741

COc1ccc(cn1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OC[C@@H](C)O)cn2ncc(C#N)c12 |r|

BDBM296746

COc1ccc(cn1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OC[C@H](C)O)cn2ncc(C#N)c12 |r|

BDBM284652

COc1ccc(cn1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296755

COc1ccc(cn1)C(=O)N1C2COCC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296750

COc1ccc(cn1)C(=O)N1CC2CC(C1)N2c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296802

COc1ccc(cn1)C(=O)N1CCCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296542

COc1ccc(cn1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM315378

COc1ccc(cn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296801

COc1ccc(cn1)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296689

COc1ccc(cn1)S(=O)(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296619

COc1ccc(cn1)[C@@H](N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12)C(F)(F)F |r|

BDBM296620

COc1ccc(cn1)[C@H](N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12)C(F)(F)F |r|

BDBM296655

COc1ccc(nc1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305113

COc1cccc(C(=O)NC2(C)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1C

BDBM305733

COc1cccc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM296435

COc1cccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1

BDBM284664

COc1cccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cn[nH]c2)n1

BDBM284440

COc1cccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)c1

BDBM284389

COc1cccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)n1

BDBM305191

COc1cccc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1 |r|

BDBM305053

COc1cccc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296668

COc1cccc(n1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305055

COc1cccc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305052

COc1ccccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305727

COc1ccccc1CC1(O)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284441

COc1ccccc1CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284372

COc1ccccc1N(C)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305068

COc1cccnc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284453

COc1cccnc1CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296596

COc1ccnc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM296558

COc1ccnc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1F

BDBM305250

COc1ccnc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM305178

COc1ccnc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM296665

COc1ccnc(c1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305074

COc1ccnc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296616

COc1cnc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c(F)c1

BDBM296550

COc1cnc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296739

COc1cnc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@@H](C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM296742

COc1cnc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@H](C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM296759

COc1cnc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305240

COc1cnc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305162

COc1cnc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296630

COc1cnc(cn1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296433

COc1cncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM284432

COc1cncc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)c1

BDBM305144

COc1cncc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM305194

COc1cncc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1 |r|

BDBM296662

COc1cncc(c1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305199

COc1nc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)ccc1F |r|

BDBM296551

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1C

BDBM296440

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1Cl

BDBM296441

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1F

BDBM296560

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296555

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)s1

BDBM296764

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(Cl)c23)cc1F

BDBM296702

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCN3CCOCC3)cn3ncc(C#N)c23)cc1C

BDBM296703

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCCN3CCOCC3)cn3ncc(C#N)c23)cc1Cl

BDBM296740

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@@H](C)O)cn3ncc(C#N)c23)cc1F |r|

BDBM296744

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@H](C)O)cn3ncc(C#N)c23)cc1Cl |r|

BDBM296743

COc1ncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OC[C@H](C)O)cn3ncc(C#N)c23)cc1F |r|

BDBM296758

COc1ncc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1F

BDBM296814

COc1ncc(CN2C3CC2CN(C3)c2cnc(cn2)-c2cc(OCCN3CCOCC3)cn3ncc(C#N)c23)cc1Cl

BDBM296819

COc1ncc(CN2C3CC2CN(C3)c2ncc(cn2)-c2cc(OCCN3CCOCC3)cn3ncc(C#N)c23)cc1Cl

BDBM296806

COc1ncc(CN2CCCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1F

BDBM284641

COc1ncc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cc1C

BDBM284632

COc1ncc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cc1Cl

BDBM284631

COc1ncc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cc1F

BDBM305073

COc1ncc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284447

COc1ncc(F)cc1CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305248

COc1ncc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1Cl

BDBM305242

COc1ncc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1F

BDBM305172

COc1ncc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1Cl

BDBM305158

COc1ncc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1F

BDBM305164

COc1ncc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM305197

COc1ncc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1Cl |r|

BDBM305195

COc1ncc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1 |r|

BDBM296672

COc1ncc(cc1C)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296629

COc1ncc(cc1Cl)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296516

COc1ncc(cc1F)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284653

COc1ncc(cc1F)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296438

COc1nccc(F)c1CN1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284442

COc1ncccc1CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305252

COc1nnc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1C

BDBM283987

C[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1 |r|

BDBM284296

C[C@@H](CO)Cn1cc(cn1)-c1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)CC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM284572

C[C@@H](CO)Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N |r|

BDBM284411

C[C@@H](N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1 |r|

BDBM284243

C[C@@H](NC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)C(F)(F)F |r|

BDBM284223

C[C@@H](NC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)C(F)(F)F |r|

BDBM284628

C[C@@H](NC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccc(F)cc1 |r|

BDBM284022

C[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284171

C[C@@H](O)C(=O)NC1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284045

C[C@@H](O)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284148

C[C@@H](O)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM315464

C[C@@H](O)COc1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)Cc2ccc(F)cn2)c2c(cnn2c1)C#N |r|

BDBM315463

C[C@@H](O)COc1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM305399

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CC(C2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305398

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(C)nn2)c2c(cnn2c1)C#N |r|

BDBM305392

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305739

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccn3)CC2)c2c(cnn2c1)C#N |r|

BDBM305741

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3Cl)CC2)c2c(cnn2c1)C#N |r|

BDBM305740

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3F)CC2)c2c(cnn2c1)C#N |r|

BDBM296383

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2ccc(F)cn2)c2c(cnn2c1)C#N |r|

BDBM296382

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM296388

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)C(C)C)c2c(cnn2c1)C#N |r|

BDBM296386

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccc(Cl)cc2)c2c(cnn2c1)C#N |r|

BDBM296385

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccc(F)cc2)c2c(cnn2c1)C#N |r|

BDBM296384

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296391

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(Cl)cn3)CC2)c2c(cnn2c1)C#N |r|

BDBM296206

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N |r|

BDBM296390

C[C@@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N |r|

BDBM284295

C[C@@H](O)Cn1cc(cn1)-c1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)CC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM296416

C[C@@H](O)[C@H](C)Oc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284139

C[C@@H]([C@@H](O)c1ccccc1)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM305198

C[C@@H]1CN(C[C@H]1Oc1ccccn1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM283988

C[C@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1 |r|

BDBM284297

C[C@H](CO)Cn1cc(cn1)-c1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)CC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM284573

C[C@H](CO)Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N |r|

BDBM284412

C[C@H](N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)c1ccccc1 |r|

BDBM284221

C[C@H](NC(=O)C1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1)C(F)(F)F |r|

BDBM284020

C[C@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284170

C[C@H](O)C(=O)NC1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284047

C[C@H](O)CC(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284147

C[C@H](O)CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM296745

C[C@H](O)COc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(OC(F)F)nc2)c2c(cnn2c1)C#N |r|

BDBM305393

C[C@H](O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N |r|

BDBM305742

C[C@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ccccn3)CC2)c2c(cnn2c1)C#N |r|

BDBM305744

C[C@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3Cl)CC2)c2c(cnn2c1)C#N |r|

BDBM305743

C[C@H](O)COc1cc(-c2ccc(nc2)N2CCC(O)(Cc3ncccc3F)CC2)c2c(cnn2c1)C#N |r|

BDBM296395

C[C@H](O)COc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296400

C[C@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(Cl)cn3)CC2)c2c(cnn2c1)C#N |r|

BDBM296398

C[C@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N |r|

BDBM284294

C[C@H](O)Cn1cc(cn1)-c1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)CC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM284155

C[C@H](O)[C@@H](C)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284137

C[C@H]([C@H](O)c1ccccc1)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM296643

C[C@H]1CCC(CC1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r,wU:1.0,(11.34,-.83,;10,-1.6,;10,-3.14,;8.67,-3.91,;7.34,-3.14,;7.34,-1.6,;8.67,-.83,;6,-3.91,;6,-5.45,;4.67,-3.14,;3.33,-3.91,;3.33,-2.37,;4.67,-1.6,;3.33,-.83,;2,-1.6,;2,-3.14,;.67,-.83,;-.67,-1.6,;-2,-.83,;-2,.71,;-.67,1.48,;.67,.71,;-3.33,1.48,;-4.67,.71,;-6,1.48,;-7.34,.71,;-8.67,1.48,;-10,.71,;-10.77,-.63,;-9.23,-.63,;-11.34,1.48,;-6,3.02,;-4.67,3.79,;-4.35,5.29,;-2.82,5.45,;-2.19,4.05,;-.7,3.65,;.79,3.25,;-3.33,3.02,)|

BDBM284077

C[N]1=CC(=CN1)c1cc(-c2ccc(nc2)N2CCN(CC2)S(=O)(=O)CC2CC2)c2c(cnn2c1)C#N |c:3,t:1|

BDBM296573

Cc1c(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)ncn1C

BDBM284425

Cc1c(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cnn1C

BDBM305056

Cc1c(Cl)cccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305129

Cc1c(Cl)cncc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305037

Cc1c(F)cccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305132

Cc1c(cnn1C)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296587

Cc1c[nH]c(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1

BDBM305082

Cc1cc(=O)cc(C(=O)NC2(C)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1C

BDBM305124

Cc1cc(C(=O)NC2(C)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c(Cl)cn1

BDBM305131

Cc1cc(C(=O)NC2(C)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c(F)cn1

BDBM284391

Cc1cc(C)nc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)n1

BDBM305087

Cc1cc(C)nc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305125

Cc1cc(C)nc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296600

Cc1cc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc(C)n1

BDBM296582

Cc1cc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)ccn1

BDBM296601

Cc1cc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)no1

BDBM284426

Cc1cc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)no1

BDBM305077

Cc1cc(F)ccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284592

Cc1cc([nH]n1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284596

Cc1cc([nH]n1)-c1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM305042

Cc1cc(cc(C)n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305118

Cc1cc(ccn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284269

Cc1cc(cnc1N1CCN(CC1)C(=O)CC(C)(C)C)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284267

Cc1cc(cnc1N1CCN(CC1)C(=O)CC(C)(C)O)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284270

Cc1cc(cnc1N1CCN(CC1)C(=O)N1CCCC1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284265

Cc1cc(cnc1N1CCN(CC1)C(=O)OC(C)(C)C)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284268

Cc1cc(cnc1N1CCN(CC1)C(=O)[C@H](O)c1ccccc1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1 |r|

BDBM284266

Cc1cc(cnc1N1CCNCC1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284300

Cc1cc(n[nH]1)-c1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)CC(C)(C)C)c2c(cnn2c1)C#N

BDBM284593

Cc1cc(nn1C)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284608

Cc1cc(nn1C)-c1cc(-c2ccc(nc2)N2CCN(Cc3ncccn3)CC2)c2c(cnn2c1)C#N

BDBM284597

Cc1cc(nn1C)-c1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM284027

Cc1cc(no1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284591

Cc1cc(on1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284599

Cc1cc(on1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284595

Cc1cc(on1)-c1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM305127

Cc1ccc(=O)[nH]c1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305072

Cc1ccc(C)c(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM283992

Cc1ccc(CC(=O)N2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM305729

Cc1ccc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1

BDBM296598

Cc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296563

Cc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1

BDBM305768

Cc1ccc(Cl)c(n1)C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305057

Cc1ccc(Cl)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305270

Cc1ccc(F)c(N[C@@H]2[C@H]3C[C@@H]2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1 |r|

BDBM305117

Cc1ccc(F)c(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305078

Cc1ccc(F)c(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305468

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(O)cn2ncc(C#N)c12

BDBM305046

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305291

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC2(C)CNC2)cn2ncc(C#N)c12

BDBM305286

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12

BDBM305289

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCCC2)cn2ncc(C#N)c12

BDBM305293

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCNCC2)cn2ncc(C#N)c12

BDBM305290

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305295

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OC[C@@H]2CNCCO2)cn2ncc(C#N)c12 |r|

BDBM305678

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305665

Cc1ccc(F)cc1C(=O)NC1(C)CCN(CC1)c1ncc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305181

Cc1ccc(F)cc1C(=O)NC1(C)CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305219

Cc1ccc(F)cc1C(=O)N[C@@]1(C)CCN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM305212

Cc1ccc(F)cc1C(=O)N[C@]1(C)CCN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12 |r|

BDBM305034

Cc1ccc(F)cc1CNC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305284

Cc1ccc(F)cc1NC(=O)C1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305254

Cc1ccc(OC2CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1

BDBM305145

Cc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1

BDBM305149

Cc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1

BDBM305159

Cc1ccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1

BDBM284306

Cc1ccc(cc1)[C@@H](O)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2nccc12)-c1cnn(C)c1 |r|

BDBM305075

Cc1ccc(cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12)C#N

BDBM296637

Cc1ccc(cc1F)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296656

Cc1ccc(cn1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305015

Cc1ccc(cn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296651

Cc1ccc(nc1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305099

Cc1ccc(nc1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305719

Cc1ccc(nn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305115

Cc1cccc(C)c1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284460

Cc1cccc(C)c1CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305728

Cc1cccc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM305732

Cc1cccc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1

BDBM296436

Cc1cccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1

BDBM284423

Cc1cccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)n1

BDBM305085

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM316026

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1ccc(nc1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305765

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(O)cn2ncc(C#N)c12

BDBM305764

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC(=O)N2CCCC2)cn2ncc(C#N)c12

BDBM305667

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305687

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC2(F)CCNC2)cn2ncc(C#N)c12

BDBM305682

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC2(F)CN(C2)C(=O)OC(C)(C)C)cn2ncc(C#N)c12

BDBM305683

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCC2(F)CNC2)cn2ncc(C#N)c12

BDBM305762

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCC(C)(C)O)cn2ncc(C#N)c12

BDBM305763

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CC(F)(F)C2)cn2ncc(C#N)c12

BDBM305674

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCC2)cn2ncc(C#N)c12

BDBM305675

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCCC2)cn2ncc(C#N)c12

BDBM305679

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCN(CC2)C(=O)OC(C)(C)C)cn2ncc(C#N)c12

BDBM305680

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCNCC2)cn2ncc(C#N)c12

BDBM305676

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305672

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OC[C@@H]2CNCCO2)cn2ncc(C#N)c12 |r|

BDBM305670

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OC[C@H]2CNCCO2)cn2ncc(C#N)c12 |r|

BDBM305669

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(cn1)-c1cc(OCc2cn(C)cn2)cn2ncc(C#N)c12

BDBM305716

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1cnc(nc1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305664

Cc1cccc(Cl)c1C(=O)NC1(C)CCN(CC1)c1ncc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305040

Cc1cccc(F)c1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305141

Cc1cccc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM305192

Cc1cccc(O[C@H]2CCN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1 |r|

BDBM296654

Cc1cccc(n1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305096

Cc1cccc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305050

Cc1ccccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305731

Cc1ccccc1CC1(O)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305156

Cc1ccccc1OC1CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296653

Cc1cccnc1C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305108

Cc1cccnc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284428

Cc1cccnc1CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305148

Cc1cccnc1OC1CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284433

Cc1ccnc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)c1

BDBM305177

Cc1ccnc(OC2CN(C2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM296660

Cc1ccnc(c1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305103

Cc1ccnc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305120

Cc1ccnc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296657

Cc1ccncc1C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305111

Cc1ccncc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305717

Cc1ccnnc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305720

Cc1cnc(C)c(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305734

Cc1cnc(CC2(O)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296584

Cc1cnc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296588

Cc1cnc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1C

BDBM284434

Cc1cnc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM315629

Cc1cnc(N[C@@H]2[C@H]3C[C@@H]2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nc1 |r|

BDBM284039

Cc1cnc(cn1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296554

Cc1cncc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM284421

Cc1cncc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)n1

BDBM296667

Cc1cncc(c1)C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305112

Cc1cncc(c1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284617

Cc1cnn2cc(cc(-c3ccc(nc3)N3CCN(CC3)C(=O)OC(C)(C)C)c12)-c1cnn(C)c1

BDBM284619

Cc1cnn2cc(cc(-c3ccc(nc3)N3CCN(CC3)C(=O)[C@H](O)c3ccccc3)c12)-c1cnn(C)c1 |r|

BDBM284620

Cc1cnn2cc(cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c12)-c1cnn(C)c1

BDBM284621

Cc1cnn2cc(cc(-c3ccc(nc3)N3CCN(Cc4ccccn4)CC3)c12)-c1cnn(C)c1

BDBM284708

Cc1cnn2cc(cc(-c3ccc(nc3)N3CCN(Cc4ncccn4)CC3)c12)-c1cnn(C)c1

BDBM284618

Cc1cnn2cc(cc(-c3ccc(nc3)N3CCNCC3)c12)-c1cnn(C)c1

BDBM296576

Cc1nc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1C

BDBM296443

Cc1nc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)co1

BDBM305135

Cc1nc(co1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284455

Cc1ncc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM305071

Cc1ncc(Cl)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284682

Cc1ncc(o1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284683

Cc1ncc(o1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284598

Cc1ncc(o1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284687

Cc1ncc(o1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM284594

Cc1ncc(o1)-c1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM284457

Cc1nccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)n1

BDBM305269

Cc1nccc(N[C@@H]2[C@H]3C[C@@H]2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)n1 |r|

BDBM296659

Cc1ncccc1C(=O)N1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305107

Cc1ncccc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305718

Cc1nccnc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305137

Cc1ncn(C)c1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305121

Cc1ncncc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284585

Cc1nn(C)c(C)c1-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284031

Cc1nn(C)cc1C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305134

Cc1nn(C)cc1C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296574

Cc1nn(C)cc1CN1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284430

Cc1nn(C)cc1CN1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM284588

Cc1nn(cc1-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N)C(C)(C)C

BDBM296614

Cc1nnc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)o1

BDBM296569

Cc1noc(C)c1CN1C2CC1CN(C2)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305261

Cn1c(nc2ccccc12)C1CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296570

Cn1cc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1

BDBM296571

Cn1cc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)nn1

BDBM284438

Cn1cc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)cn1

BDBM284589

Cn1cc(c(n1)C1CC1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284590

Cn1cc(c(n1)C1CC1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM284292

Cn1cc(cn1)-c1cc(-c2ccc(cc2)C2CCN(CC2)C(=O)CC(C)(C)C)c2c(cnn2c1)C#N

BDBM284290

Cn1cc(cn1)-c1cc(-c2ccc(cc2)C2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284291

Cn1cc(cn1)-c1cc(-c2ccc(cc2)C2CCNCC2)c2c(cnn2c1)C#N

BDBM284284

Cn1cc(cn1)-c1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)CC(C)(C)C)c2c(cnn2c1)C#N

BDBM284283

Cn1cc(cn1)-c1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)CO)c2c(cnn2c1)C#N

BDBM284280

Cn1cc(cn1)-c1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284287

Cn1cc(cn1)-c1cc(-c2ccc(cc2)N2CCN(CC2)S(C)(=O)=O)c2c(cnn2c1)C#N

BDBM284703

Cn1cc(cn1)-c1cc(-c2ccc(cc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM284704

Cn1cc(cn1)-c1cc(-c2ccc(cc2)N2CCN(Cc3ncccn3)CC2)c2c(cnn2c1)C#N

BDBM284281

Cn1cc(cn1)-c1cc(-c2ccc(cc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM284610

Cn1cc(cn1)-c1cc(-c2ccc(cn2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284562

Cn1cc(cn1)-c1cc(-c2ccc(nc2)C2CCCN(Cc3ccccc3)C2)c2c(cnn2c1)C#N

BDBM284564

Cn1cc(cn1)-c1cc(-c2ccc(nc2)C2CCN(CC3CCOCC3)C2)c2c(cnn2c1)C#N

BDBM284563

Cn1cc(cn1)-c1cc(-c2ccc(nc2)C2CCN(Cc3ccccc3)C2)c2c(cnn2c1)C#N

BDBM284560

Cn1cc(cn1)-c1cc(-c2ccc(nc2)C2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284565

Cn1cc(cn1)-c1cc(-c2ccc(nc2)C2CCN(Cc3ncccn3)C2)c2c(cnn2c1)C#N

BDBM284561

Cn1cc(cn1)-c1cc(-c2ccc(nc2)C2CN(Cc3ccccc3)C2)c2c(cnn2c1)C#N

BDBM284477

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2C3CC2CN(Cc2ccccc2)C3)c2c(cnn2c1)C#N

BDBM284330

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2C3CCC2CC3)c2c(Cl)cnn2c1 |THB:12:15:21.20:17.18|

BDBM284324

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2C3CCC2CN(C3)C(=O)OC(C)(C)C)c2c(Cl)cnn2c1

BDBM284478

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2C3CCC2CN(Cc2ccccc2)C3)c2c(cnn2c1)C#N

BDBM284325

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2C3CCC2CNC3)c2c(Cl)cnn2c1

BDBM284556

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC(C2)C(O)=O)c2c(cnn2c1)C#N

BDBM284558

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC(CC(O)=O)C2)c2c(cnn2c1)C#N

BDBM284538

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCCCN3)c2c(cnn2c1)C#N

BDBM284510

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCCCN3C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284509

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCCN(C3)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284539

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCCN3)c2c(cnn2c1)C#N

BDBM284511

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCCN3C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284512

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCCN3C(=O)OCc2ccccc2)c2c(cnn2c1)C#N

BDBM284537

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCCNC3)c2c(cnn2c1)C#N

BDBM284213

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCN(CC3)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284475

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCN(Cc2ccccc2)CC3)c2c(cnn2c1)C#N

BDBM284536

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCNCC3)c2c(cnn2c1)C#N

BDBM284515

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCOC3)c2c(cnn2c1)C#N

BDBM284514

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(C2)CCOCC3)c2c(cnn2c1)C#N

BDBM284513

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(CN(C3)C(=O)OC(C)(C)C)C2)c2c(cnn2c1)C#N

BDBM284545

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3(CN(Cc4ccccc4)C3)C2)c2c(cnn2c1)C#N

BDBM284328

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3CC(C2)N3)c2c(Cl)cnn2c1

BDBM284656

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)Cc2ccc(F)cn2)c2c(cnn2c1)C#N

BDBM284327

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3CC(C2)N3C(=O)OC(C)(C)C)c2c(Cl)cnn2c1

BDBM284476

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccccc2)c2c(cnn2c1)C#N

BDBM284658

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccccn2)c2c(cnn2c1)C#N

BDBM284164

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3CCC(C2)N3)c2c(cnn2c1)C#N

BDBM284163

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3CCC(C2)N3C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284474

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC3CCC(C2)N3Cc2ccccc2)c2c(cnn2c1)C#N

BDBM284240

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(C)(CC2)C(=O)NCCC(F)(F)F)c2c(cnn2c1)C#N

BDBM284191

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284192

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(C)(N)CC2)c2c(cnn2c1)C#N

BDBM284520

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(C2)c2ccccc2)c2c(cnn2c1)C#N

BDBM284238

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)C(=O)N2CCCC2)c2c(cnn2c1)C#N

BDBM284228

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)C(=O)NC2CC(F)(F)C2)c2c(cnn2c1)C#N

BDBM284233

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)C(=O)NCC(F)(F)F)c2c(cnn2c1)C#N

BDBM284232

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)C(=O)NCCC(F)(F)F)c2c(cnn2c1)C#N

BDBM284550

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)C(=O)NOC(C)(C)C)c2c(cnn2c1)C#N

BDBM284548

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)C(=O)NOCC2CC2)c2c(cnn2c1)C#N

BDBM284551

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)C(=O)NOCCO)c2c(cnn2c1)C#N

BDBM284179

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)N2CCCC2=O)c2c(cnn2c1)C#N

BDBM284181

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)N2CCOC2=O)c2c(cnn2c1)C#N

BDBM284180

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)N2CC[C@H](O)C2=O)c2c(cnn2c1)C#N |r|

BDBM284169

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)C(C)(C)O)c2c(cnn2c1)C#N

BDBM284166

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284172

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)[C@@H]2CCCO2)c2c(cnn2c1)C#N |r|

BDBM284168

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)[C@H]2CCCO2)c2c(cnn2c1)C#N |r|

BDBM284174

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)NC(=O)c2ccccc2)c2c(cnn2c1)C#N

BDBM284494

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM284496

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccc(Cl)cc2)c2c(cnn2c1)C#N

BDBM284495

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccc2)c2c(cnn2c1)C#N

BDBM284552

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)S(C)(=O)=O)c2c(cnn2c1)C#N

BDBM284553

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)S(O)(=O)=O)c2c(cnn2c1)C#N

BDBM284521

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(CC2)c2ccc(Cl)cc2)c2c(cnn2c1)C#N

BDBM284523

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(Cc3ccc(Cl)cc3)CC2)c2c(cnn2c1)C#N

BDBM284522

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284555

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM284167

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(N)CC2)c2c(cnn2c1)C#N

BDBM284518

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(O)(C2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM284497

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(O)(CC2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM284186

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC(O)CC2)c2c(cnn2c1)C#N

BDBM284505

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(C2)CCCN(C3)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284532

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(C2)CCCNC3)c2c(cnn2c1)C#N

BDBM284516

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(C2)CCCOC3)c2c(cnn2c1)C#N

BDBM284504

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(C2)CCN(CC3)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284531

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(C2)CCNCC3)c2c(cnn2c1)C#N

BDBM284479

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CC(C3)C(=O)C3CC3)CC2)c2c(cnn2c1)C#N

BDBM284503

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CC(C3)NC(=O)OC(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM284530

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CC(N)C3)CC2)c2c(cnn2c1)C#N

BDBM284491

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCCN(C3)C(=O)OC(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM284534

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCCN3)C2)c2c(cnn2c1)C#N

BDBM284527

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCCN3)CC2)c2c(cnn2c1)C#N

BDBM284507

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCCN3C(=O)OC(C)(C)C)C2)c2c(cnn2c1)C#N

BDBM284500

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCCN3C(=O)OC(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM284506

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCN(C3)C(=O)OC(C)(C)C)C2)c2c(cnn2c1)C#N

BDBM284194

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCN(C3)C(=O)OC(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM284498

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCN(CC3)C(=O)OC(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM284529

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCN3)CC2)c2c(cnn2c1)C#N

BDBM284502

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCN3C(=O)OC(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM284533

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCNC3)C2)c2c(cnn2c1)C#N

BDBM284195

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCNC3)CC2)c2c(cnn2c1)C#N

BDBM284525

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCNCC3)CC2)c2c(cnn2c1)C#N

BDBM284517

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CCOC3)C2)c2c(cnn2c1)C#N

BDBM284480

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)C3CCC3)CC2)c2c(cnn2c1)C#N

BDBM284209

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)C3CCCC3)CC2)c2c(cnn2c1)C#N

BDBM284482

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)C3CCCCC3)CC2)c2c(cnn2c1)C#N

BDBM284484

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)CC3CCCC3)CC2)c2c(cnn2c1)C#N

BDBM284485

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)CC3CCCCC3)CC2)c2c(cnn2c1)C#N

BDBM284208

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284487

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)N3CCCC3)CC2)c2c(cnn2c1)C#N

BDBM284508

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)OC(C)(C)C)C2)c2c(cnn2c1)C#N

BDBM284204

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)OC(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM284486

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)OC3CCCC3)CC2)c2c(cnn2c1)C#N

BDBM284207

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(C3)C(=O)c3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284544

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(Cc4ccccc4)C3)C2)c2c(cnn2c1)C#N

BDBM284490

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CN(Cc4ccccc4)C3)CC2)c2c(cnn2c1)C#N

BDBM284535

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CNC3)C2)c2c(cnn2c1)C#N

BDBM284205

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCC3(CNC3)CC2)c2c(cnn2c1)C#N

BDBM284329

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCCC2)c2c(Cl)cnn2c1

BDBM284519

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCCC2c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM284528

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCCC3(CCCN3)C2)c2c(cnn2c1)C#N

BDBM284501

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCCC3(CCCN3C(=O)OC(C)(C)C)C2)c2c(cnn2c1)C#N

BDBM284198

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCCC3(CCN(C3)C(=O)OC(C)(C)C)C2)c2c(cnn2c1)C#N

BDBM284499

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCCC3(CCN(CC3)C(=O)OC(C)(C)C)C2)c2c(cnn2c1)C#N

BDBM284199

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCCC3(CCNC3)C2)c2c(cnn2c1)C#N

BDBM284526

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCCC3(CCNCC3)C2)c2c(cnn2c1)C#N

BDBM284159

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(C(=O)CC(C)(C)C)C3(CC3)C2)c2c(cnn2c1)C#N

BDBM284158

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(C(=O)CC(C)(C)O)C3(CC3)C2)c2c(cnn2c1)C#N

BDBM284156

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(C(=O)OC(C)(C)C)C3(CC3)C2)c2c(cnn2c1)C#N

BDBM284135

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC(=O)N3CCCC3)CC2)c2c(cnn2c1)C#N

BDBM284146

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC(C)(C)O)CC2)c2c(cnn2c1)C#N

BDBM284409

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC(F)(F)F)CC2)c2c(cnn2c1)C#N

BDBM284408

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC(F)F)CC2)c2c(cnn2c1)C#N

BDBM284138

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC(O)C(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM284144

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC(O)c3c(F)cccc3F)CC2)c2c(cnn2c1)C#N

BDBM284142

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC(O)c3ccc(Cl)cc3)CC2)c2c(cnn2c1)C#N

BDBM284154

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC(O)c3ccc(F)cc3)CC2)c2c(cnn2c1)C#N

BDBM284024

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(C)(C)C)c2c(cnn2c1)C#N

BDBM284021

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(C)(C)O)c2c(cnn2c1)C#N

BDBM284016

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(C)(C)c2ccccc2)c2c(cnn2c1)C#N

BDBM284049

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(C)(F)F)c2c(cnn2c1)C#N

BDBM283989

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(CO)c2ccccc2)c2c(cnn2c1)C#N

BDBM284358

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(N2CCCCC2)c2ccccc2)c2c(cnn2c1)C#N

BDBM284353

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(N2CCOCC2)c2ccccc2)c2c(cnn2c1)C#N

BDBM284308

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(O)c2c(F)cccc2F)c2ccnn2c1

BDBM284309

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(O)c2cc(F)cc(F)c2)c2ccnn2c1

BDBM284307

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(O)c2ccc(F)cc2F)c2ccnn2c1

BDBM283983

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C(O)c2ccccc2F)c2c(cnn2c1)C#N

BDBM284338

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)C#N)c2c(cnn2c1)C#N

BDBM284336

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM284331

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)c2ccc(Cl)cc2)c2c(cnn2c1)C#N

BDBM284333

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)c2ccc(Cl)cc2Cl)c2c(cnn2c1)C#N

BDBM284335

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)c2ccc(F)cc2)c2c(cnn2c1)C#N

BDBM284346

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)c2cccc(Cl)c2)c2c(cnn2c1)C#N

BDBM284339

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)c2cccc(F)c2)c2c(cnn2c1)C#N

BDBM284015

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)c2ccccc2)c2c(cnn2c1)C#N

BDBM284349

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)c2ccccn2)c2c(cnn2c1)C#N

BDBM284359

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)c2cccnc2)c2c(cnn2c1)C#N

BDBM284340

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CC2)c2cnccn2)c2c(cnn2c1)C#N

BDBM284017

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CCC2)c2ccccc2)c2c(cnn2c1)C#N

BDBM284014

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CCCC2)c2ccccc2)c2c(cnn2c1)C#N

BDBM284018

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CCCCC2)c2ccccc2)c2c(cnn2c1)C#N

BDBM284332

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CCOCC2)c2ccccc2)c2c(cnn2c1)C#N

BDBM284337

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(CO)CC2)c2c(cnn2c1)C#N

BDBM284071

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2(O)CC2)c2c(cnn2c1)C#N

BDBM284058

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2CC2)c2c(cnn2c1)C#N

BDBM284003

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2CCCC2)c2c(cnn2c1)C#N

BDBM284345

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2CCCCN2)c2c(cnn2c1)C#N

BDBM284037

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2CCCNC2)c2c(cnn2c1)C#N

BDBM284036

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2CCNCC2)c2c(cnn2c1)C#N

BDBM284064

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2CCOCC2)c2c(cnn2c1)C#N

BDBM284070

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C2CC[C@H](O)CC2)c2c(cnn2c1)C#N |r,wU:26.29,(-10.39,-2.64,;-9.62,-1.31,;-8.16,-.83,;-8.16,.71,;-9.62,1.18,;-10.53,-.06,;-6.83,1.48,;-5.49,.71,;-4.16,1.48,;-2.82,.71,;-2.82,-.83,;-1.49,-1.6,;-.16,-.83,;-.16,.71,;-1.49,1.48,;1.18,-1.6,;1.19,-3.14,;2.53,-3.91,;3.86,-3.14,;3.86,-1.6,;2.53,-.83,;5.19,-3.91,;5.19,-5.45,;6.53,-3.14,;7.86,-3.91,;9.2,-3.14,;9.2,-1.6,;10.53,-.83,;7.86,-.83,;6.53,-1.6,;-4.16,3.02,;-3.01,4.05,;-3.64,5.45,;-5.17,5.29,;-5.49,3.79,;-6.83,3.02,;-1.53,3.65,;-.04,3.25,)|

BDBM284321

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CC(C)(C)C)c2c(Cl)cnn2c1

BDBM284055

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CC(C)(C)C)c2c(cnn2c1)C#N

BDBM284069

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CC(C)(C)O)c2c(cnn2c1)C#N

BDBM284067

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CC2CC2)c2c(cnn2c1)C#N

BDBM284052

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CC2CCOC2)c2c(cnn2c1)C#N

BDBM284066

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CC2CCOCC2)c2c(cnn2c1)C#N

BDBM283893

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CCS(C)(=O)=O)c2c(cnn2c1)C#N

BDBM284033

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CCc2cccnc2)c2c(cnn2c1)C#N

BDBM283991

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CN(C(=O)OC(C)(C)C)C(C)(C)C)c2c(cnn2c1)C#N

BDBM284054

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CN2CCCC2)c2c(cnn2c1)C#N

BDBM284352

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CN2CCOCC2)c2c(cnn2c1)C#N

BDBM284004

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)CNC(C)(C)C)c2c(cnn2c1)C#N

BDBM283980

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C[C@@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284013

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C[C@H](N)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM283990

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C[C@H](NC(=O)OC(C)(C)C)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM283981

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)C[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284029

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2c(F)cccc2F)c2c(cnn2c1)C#N

BDBM284304

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2c(F)cccc2F)c2ccnn2c1

BDBM284350

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2ccc(F)cn2)c2c(cnn2c1)C#N

BDBM284347

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2ccc(OC(F)(F)F)cc2)c2c(cnn2c1)C#N

BDBM284355

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2ccc(cc2)C#N)c2c(cnn2c1)C#N

BDBM284068

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2ccccc2)c2c(cnn2c1)C#N

BDBM283978

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2ccccn2)c2c(cnn2c1)C#N

BDBM284061

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2cccnc2)c2c(cnn2c1)C#N

BDBM284032

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2ccn(C)n2)c2c(cnn2c1)C#N

BDBM284002

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Cc2ccnn2C)c2c(cnn2c1)C#N

BDBM284085

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2C3CCC2CC3)c2c(cnn2c1)C#N

BDBM284374

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CC3C(C2)C3(C)C)c2c(cnn2c1)C#N

BDBM284370

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CC3CC3C2)c2c(cnn2c1)C#N

BDBM284113

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CC3COCC3C2)c2c(cnn2c1)C#N

BDBM284108

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCC(C)(C)C2)c2c(cnn2c1)C#N

BDBM284381

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCC(C2)C(F)(F)F)c2c(cnn2c1)C#N

BDBM284378

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCC(C2)C2CC2)c2c(cnn2c1)C#N

BDBM284369

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCC(C2)N2CCOCC2)c2c(cnn2c1)C#N

BDBM284091

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCC(F)(F)C2)c2c(cnn2c1)C#N

BDBM284105

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCC(F)(F)CC2)c2c(cnn2c1)C#N

BDBM284104

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCC(F)CC2)c2c(cnn2c1)C#N

BDBM284082

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCC(O)CC2)c2c(cnn2c1)C#N

BDBM284107

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCC3(CC3)C2)c2c(cnn2c1)C#N

BDBM284084

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCCC(F)(F)C2)c2c(cnn2c1)C#N

BDBM284106

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCCC(F)C2)c2c(cnn2c1)C#N

BDBM284114

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCCC2(C)C)c2c(cnn2c1)C#N

BDBM284115

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCCC2)c2c(cnn2c1)C#N

BDBM284083

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCCCC2)c2c(cnn2c1)C#N

BDBM284102

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCC[C@H]2C#N)c2c(cnn2c1)C#N |r|

BDBM284103

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCC[C@H]2C(F)(F)F)c2c(cnn2c1)C#N |r|

BDBM284371

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCN3CCCC3C2)c2c(cnn2c1)C#N

BDBM284109

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CCOCC2)c2c(cnn2c1)C#N

BDBM284368

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CC[C@@H](C2)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284093

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CC[C@@H](F)C2)c2c(cnn2c1)C#N |r|

BDBM284089

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CC[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM284365

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CC[C@H](C2)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284092

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CC[C@H](F)C2)c2c(cnn2c1)C#N |r|

BDBM284090

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N2CC[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM284118

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)NC(C)(C)C)c2c(cnn2c1)C#N

BDBM284121

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)NC2CC2)c2c(cnn2c1)C#N

BDBM284111

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)NC2CCOCC2)c2c(cnn2c1)C#N

BDBM284119

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)NCc2ccccc2)c2c(cnn2c1)C#N

BDBM284096

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N[C@@H]2CCOC2)c2c(cnn2c1)C#N |r|

BDBM284095

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)N[C@H]2CCOC2)c2c(cnn2c1)C#N |r|

BDBM284117

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)Nc2ccccc2)c2c(cnn2c1)C#N

BDBM284616

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(Br)cnn2c1

BDBM284315

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(Cl)cnn2c1

BDBM283818

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284301

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2ccnn2c1

BDBM284363

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H](CO)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284040

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H](N)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM283931

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H](O)Cc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM283979

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284034

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H]2CCCN2)c2c(cnn2c1)C#N |r|

BDBM284050

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H]2CCCO2)c2c(cnn2c1)C#N |r|

BDBM284038

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](N)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284051

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)C(F)(F)F)c2c(cnn2c1)C#N |r|

BDBM283982

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)Cc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284312

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2cccc(Cl)c2)c2ccnn2c1 |r|

BDBM284072

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284303

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2ccnn2c1 |r|

BDBM284310

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2Cl)c2ccnn2c1 |r|

BDBM284311

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2F)c2ccnn2c1 |r|

BDBM283986

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H]2CCC(F)(F)C2)c2c(cnn2c1)C#N |r|

BDBM284035

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H]2CCCN2)c2c(cnn2c1)C#N |r|

BDBM284048

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H]2CCCO2)c2c(cnn2c1)C#N |r|

BDBM283985

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H]2CC[C@@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM283984

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H]2CC[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM284041

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)c2c(F)cccc2F)c2c(cnn2c1)C#N

BDBM284305

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)c2c(F)cccc2F)c2ccnn2c1

BDBM284360

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)c2cc([nH]n2)C2CC2)c2c(cnn2c1)C#N

BDBM284059

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)c2ccccc2)c2c(cnn2c1)C#N

BDBM284348

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)c2ccccc2N2CCOCC2)c2c(cnn2c1)C#N

BDBM284062

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM284063

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)c2cccnc2)c2c(cnn2c1)C#N

BDBM284028

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)c2cnccn2)c2c(cnn2c1)C#N

BDBM284466

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C2CCC2)c2c(cnn2c1)C#N

BDBM284145

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C2CCCC[C@H]2O)c2c(cnn2c1)C#N |r|

BDBM284153

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C2CCC[C@H]2O)c2c(cnn2c1)C#N |r|

BDBM284492

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C2CCOC2)c2c(cnn2c1)C#N

BDBM284465

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C2CCOCC2)c2c(cnn2c1)C#N

BDBM284392

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C2CCS(=O)(=O)CC2)c2c(cnn2c1)C#N

BDBM284469

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C2COC2)c2c(cnn2c1)C#N

BDBM284149

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C2COC[C@H]2O)c2c(cnn2c1)C#N |r|

BDBM284131

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C=O)c2c(cnn2c1)C#N

BDBM284364

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)S(=O)(=O)C2(C)CC2)c2c(cnn2c1)C#N

BDBM284081

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)S(=O)(=O)C2CCOCC2)c2c(cnn2c1)C#N

BDBM284079

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)S(=O)(=O)CC(C)(C)C)c2c(cnn2c1)C#N

BDBM284128

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)S(=O)(=O)N2CCCC2)c2c(cnn2c1)C#N

BDBM284127

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)S(=O)(=O)NC(C)(C)C)c2c(cnn2c1)C#N

BDBM284322

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)S(C)(=O)=O)c2c(Cl)cnn2c1

BDBM284078

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC2)S(C)(=O)=O)c2c(cnn2c1)C#N

BDBM284449

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC3CC(F)(F)C3)CC2)c2c(cnn2c1)C#N

BDBM284384

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC3CC3)CC2)c2c(cnn2c1)C#N

BDBM284394

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC3CCCCO3)CC2)c2c(cnn2c1)C#N

BDBM284396

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC3CCOC3)CC2)c2c(cnn2c1)C#N

BDBM284456

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC3CCOCC3)CC2)c2c(cnn2c1)C#N

BDBM284467

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CC3COC3)CC2)c2c(cnn2c1)C#N

BDBM284524

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CCN)CC2)c2c(cnn2c1)C#N

BDBM284468

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CCN3CCOCC3)CC2)c2c(cnn2c1)C#N

BDBM284493

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CCNC(=O)OC(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM284410

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CCOC(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM284388

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CCOC(F)(F)F)CC2)c2c(cnn2c1)C#N

BDBM284397

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CCOC3CC3)CC2)c2c(cnn2c1)C#N

BDBM284629

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CCS(=O)(=O)c3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284130

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CCc3ccc(Cl)cc3)CC2)c2c(cnn2c1)C#N

BDBM284401

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CCc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284385

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(CCc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM284152

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(C[C@@H](O)c3ccccc3)CC2)c2c(cnn2c1)C#N |r|

BDBM284649

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(C[C@@H]3CCCCO3)CC2)c2c(cnn2c1)C#N |r|

BDBM284143

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(C[C@H](O)c3cccc(Cl)c3)CC2)c2c(cnn2c1)C#N |r|

BDBM284151

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(C[C@H](O)c3ccccc3)CC2)c2c(cnn2c1)C#N |r|

BDBM284314

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(C[C@H](O)c3ccccc3)CC2)c2ccnn2c1 |r|

BDBM284431

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3c(F)cccc3F)CC2)c2c(cnn2c1)C#N

BDBM284437

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3cc(F)cc(F)c3)CC2)c2c(cnn2c1)C#N

BDBM284419

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3cc(F)ccc3F)CC2)c2c(cnn2c1)C#N

BDBM284415

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(Cl)cc3)CC2)c2c(cnn2c1)C#N

BDBM284414

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(F)cc3)CC2)c2c(cnn2c1)C#N

BDBM284416

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(F)cc3F)CC2)c2c(cnn2c1)C#N

BDBM284452

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(F)cn3)CC2)c2c(cnn2c1)C#N

BDBM284640

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OC(F)F)nc3)CC2)c2c(cnn2c1)C#N

BDBM284639

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(OCC(F)(F)F)nc3)CC2)c2c(cnn2c1)C#N

BDBM284459

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(cc3)C#N)CC2)c2c(cnn2c1)C#N

BDBM284646

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(nc3)C#N)CC2)c2c(cnn2c1)C#N

BDBM284644

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(nc3)C(C)(C)C)CC2)c2c(cnn2c1)C#N

BDBM284645

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(nc3)C(C)(C)O)CC2)c2c(cnn2c1)C#N

BDBM284642

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccc(nc3)C(F)(F)F)CC2)c2c(cnn2c1)C#N

BDBM284445

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3cccc(Cl)c3)CC2)c2c(cnn2c1)C#N

BDBM284418

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3cccc(F)c3)CC2)c2c(cnn2c1)C#N

BDBM284458

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3cccc(c3)C#N)CC2)c2c(cnn2c1)C#N

BDBM284472

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)C(=O)C2)c2c(cnn2c1)C#N

BDBM284614

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(Cl)cnn2c1

BDBM284129

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284454

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3C#N)CC2)c2c(cnn2c1)C#N

BDBM284444

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3Cl)CC2)c2c(cnn2c1)C#N

BDBM284417

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3F)CC2)c2c(cnn2c1)C#N

BDBM284463

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM284647

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3cccn(C)c3=O)CC2)c2c(cnn2c1)C#N

BDBM284461

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3cccnc3)CC2)c2c(cnn2c1)C#N

BDBM284648

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccn(C)c(=O)c3)CC2)c2c(cnn2c1)C#N

BDBM284424

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccncc3F)CC2)c2c(cnn2c1)C#N

BDBM284420

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3cncc(Cl)c3)CC2)c2c(cnn2c1)C#N

BDBM284413

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3cncc(F)c3)CC2)c2c(cnn2c1)C#N

BDBM284443

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3cnccn3)CC2)c2c(cnn2c1)C#N

BDBM284706

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ncccn3)CC2)c2c(Cl)cnn2c1

BDBM284462

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ncccn3)CC2)c2c(cnn2c1)C#N

BDBM284427

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3nccn3C)CC2)c2c(cnn2c1)C#N

BDBM284651

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN3C(CN(Cc4ccccc4)C3=O)C2)c2c(cnn2c1)C#N

BDBM284157

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCNC3(CC3)C2)c2c(cnn2c1)C#N

BDBM284316

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCNCC2)c2c(Cl)cnn2c1

BDBM283820

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM284625

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C1CC1

BDBM284302

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCNCC2)c2ccnn2c1

BDBM284214

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CCOCC2)c2c(cnn2c1)C#N

BDBM284253

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC[C@@H](C2)C(=O)N2CCCC2)c2c(cnn2c1)C#N |r|

BDBM284252

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC[C@@H](C2)C(=O)NCCC(F)(F)F)c2c(cnn2c1)C#N |r|

BDBM284250

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC[C@H](C2)C(=O)N2CCCC2)c2c(cnn2c1)C#N |r|

BDBM284249

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2CC[C@H](C2)C(=O)NCCC(F)(F)F)c2c(cnn2c1)C#N |r|

BDBM284161

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H]2CN3)c2c(cnn2c1)C#N |r|

BDBM284162

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H]2CN3C(=O)CC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM284160

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H]2CN3C(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r|

BDBM284473

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2C[C@@H]3C[C@H]2CN3Cc2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284184

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2[C@H]3CC[C@@H]2C[C@@H](C3)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r,THB:12:15:20.21.22:17.18|

BDBM284183

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2[C@H]3CC[C@@H]2C[C@@H](N)C3)c2c(cnn2c1)C#N |r,THB:12:15:20.21.23:17.18|

BDBM284182

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2[C@H]3CC[C@@H]2C[C@H](C3)NC(=O)OC(C)(C)C)c2c(cnn2c1)C#N |r,THB:12:15:20.21.22:17.18|

BDBM284185

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2[C@H]3CC[C@@H]2C[C@H](N)C3)c2c(cnn2c1)C#N |r,THB:12:15:20.21.23:17.18|

BDBM284189

Cn1cc(cn1)-c1cc(-c2ccc(nc2)N2[C@H]3CC[C@@H]2C[C@H](O)C3)c2c(cnn2c1)C#N |r,THB:12:15:20.21.23:17.18|

BDBM284278

Cn1cc(cn1)-c1cc(-c2cnc(cn2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284277

Cn1cc(cn1)-c1cc(-c2cnc(cn2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM284272

Cn1cc(cn1)-c1cc(-c2cnc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284609

Cn1cc(cn1)-c1cc(-c2cnc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM284702

Cn1cc(cn1)-c1cc(-c2cnc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM284271

Cn1cc(cn1)-c1cc(-c2cnc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM284025

Cn1cc(cn1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM305133

Cn1cc(cn1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM284691

Cn1cc(nn1)-c1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM296609

Cn1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cc1=O

BDBM284429

Cn1ccc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)n1

BDBM284299

Cn1ccc(n1)-c1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)CC(C)(C)C)c2c(cnn2c1)C#N

BDBM284260

Cn1ccc(n1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c2c(cnn2c1)C#N

BDBM284262

Cn1ccc(n1)-c1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM284569

Cn1ccc(n1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM284261

Cn1ccc(n1)-c1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM305136

Cn1ccc(n1)C(=O)NC1(C)CCN(CC1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM305081

Cn1cccc(C(=O)NC2(C)CCN(CC2)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1=O

BDBM305440

Cn1ccnc1COc1cc(-c2ccc(nc2)N2CCC(C)(CC2)NC(=O)c2ccccn2)c2c(cnn2c1)C#N

BDBM296572

Cn1cnc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)c1

BDBM284439

Cn1cnc(CN2CCN(CC2)c2ccc(cn2)-c2cc(cn3ncc(C#N)c23)-c2cnn(C)c2)c1

BDBM305421

Cn1cnc(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccc3)c3c(cnn3c2)C#N)c1

BDBM305437

Cn1cnc(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ccccn3)c3c(cnn3c2)C#N)c1

BDBM305298

Cn1cnc(COc2cc(-c3ccc(nc3)N3CCC(C)(CC3)NC(=O)c3ncccc3Cl)c3c(cnn3c2)C#N)c1

BDBM284298

Cn1cnc(c1)-c1cc(-c2ccc(cc2)N2CCN(CC2)C(=O)CC(C)(C)C)c2c(cnn2c1)C#N

BDBM284026

Cn1cnc(c1)C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(C)c1

BDBM296561

Cn1cnc2cc(CN3C4CC3CN(C4)c3ccc(cn3)-c3cc(OCC(C)(C)O)cn4ncc(C#N)c34)ccc12

BDBM305150

Cn1nccc1OC1CN(C1)c1ccc(cn1)-c1cc(OCC(C)(C)O)cn2ncc(C#N)c12

BDBM296337

FC(F)(F)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM296201

FC(F)(F)OCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N

BDBM296336

FC(F)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM296220

FC(F)Oc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM284567

FC(F)n1cc(cn1)-c1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N

BDBM284256

FC(F)n1cc(cn1)-c1cc(-c2ccc(nc2)N2CCNCC2)c2c(cnn2c1)C#N

BDBM296203

N#Cc1cnn2cc(OC3CCOCC3)cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c12

BDBM296207

N#Cc1cnn2cc(OC3CNC3)cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c12

BDBM296350

N#Cc1cnn2cc(OCC3CCC3)cc(-c3ccc(nc3)N3CCN(Cc4ccccn4)CC3)c12

BDBM296352

N#Cc1cnn2cc(OCC3CCC3)cc(-c3ccc(nc3)N3CCN(Cc4ncccn4)CC3)c12

BDBM296204

N#Cc1cnn2cc(OCC3CCCCO3)cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c12

BDBM296209

N#Cc1cnn2cc(OCC3CNC3)cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c12

BDBM296211

N#Cc1cnn2cc(OCC3COC3)cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c12

BDBM305387

N#Cc1cnn2cc(OCCN3CCCC3)cc(-c3ccc(nc3)N3CCC(CC3)Oc3ccccn3)c12

BDBM305396

N#Cc1cnn2cc(OCCN3CCOCC3)cc(-c3ccc(nc3)N3CC(C3)Oc3ccccn3)c12

BDBM305384

N#Cc1cnn2cc(OCCN3CCOCC3)cc(-c3ccc(nc3)N3CCC(CC3)Oc3ccccn3)c12

BDBM296213

N#Cc1cnn2cc(OCCN3CCOCC3)cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c12

BDBM296357

N#Cc1cnn2cc(OCCN3CCOCC3)cc(-c3ccc(nc3)N3CCN(Cc4ncccn4)CC3)c12

BDBM296361

N#Cc1cnn2cc(OCc3ncco3)cc(-c3ccc(nc3)N3CCN(Cc4ccccn4)CC3)c12

BDBM284571

N#Cc1cnn2cc(cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c12)-c1cn[nH]c1

BDBM284575

N#Cc1cnn2cc(cc(-c3ccc(nc3)N3CCN(Cc4ccccc4)CC3)c12)-c1cnn(c1)C1CNC1

BDBM305389

NC(=O)COc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305002

N[C@H]1CCCN(C1)c1ccc(cn1)-c1cc(OCCO)cn2ncc(C#N)c12 |r|

BDBM305388

O=C1CCCN1CCOc1cc(-c2ccc(nc2)N2CCC(CC2)Oc2ccccn2)c2c(cnn2c1)C#N

BDBM305395

OC1(Cc2ccccc2)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305394

OC1(Cc2ccccn2)CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM305749

OC1(Cc2ncccc2F)CCN(CC1)c1cnc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12

BDBM296453

OCCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296452

OCCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296458

OCCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(Cl)cn3)CC2)c2c(cnn2c1)C#N

BDBM296460

OCCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(F)cn3)CC2)c2c(cnn2c1)C#N

BDBM296377

OCCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccc(Cl)cn2)c2c(cnn2c1)C#N

BDBM296378

OCCOc1cc(-c2ccc(nc2)N2CC3CC(C2)N3Cc2ccccn2)c2c(cnn2c1)C#N

BDBM296379

OCCOc1cc(-c2ccc(nc2)N2CCC3(CNC3)CC2)c2c(cnn2c1)C#N

BDBM305001

OCCOc1cc(-c2ccc(nc2)N2CCC[C@H](O)C2)c2c(cnn2c1)C#N |r|

BDBM296368

OCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296367

OCCOc1cc(-c2ccc(nc2)N2CCN(CC2)C(=O)[C@H](O)c2ccccc2)c2c(cnn2c1)C#N |r|

BDBM296373

OCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(Cl)cn3)CC2)c2c(cnn2c1)C#N

BDBM296375

OCCOc1cc(-c2ccc(nc2)N2CCN(Cc3ccc(F)cn3)CC2)c2c(cnn2c1)C#N

BDBM296463

OC[C@H](O)COc1cc(-c2ccc(nc2)N2CCN(Cc3ccccn3)CC2)c2c(cnn2c1)C#N |r|

BDBM296355

O[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(OCCN2CCOCC2)cn2ncc(C#N)c12)c1ccccc1 |r|

BDBM284258

O[C@@H](C(=O)N1CCN(CC1)c1ccc(cn1)-c1cc(cn2ncc(C#N)c12)-c1cnn(c1)C(F)F)c1ccccc1 |r|

BDBM296194

Oc1cc(-c2ccc(nc2)N2CCN(Cc3ccccc3)CC2)c2c(cnn2c1)C#N