Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 0.247nMAssay Description:In vitro inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor by Panlabs assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity toward 5-HT2C receptor evaluated by displacement of [3H]-5-HT radioligand More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, binding (Experi...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 0.515nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 0.590nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 0.791nMAssay Description:In vitro inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor (Experiment 2)More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, bindingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor (Expe...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]GTP-gamma-S, binding (Experi...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity toward 5-HT2C receptor evaluated by displacement of [3H]-5-HT radioligand More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity toward 5-HT2C receptor evaluated by displacement of [3H]-5-HT radioligand More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity toward 5-HT2C receptor evaluated by displacement of [3H]-5-HT radioligand More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]5HT from human 5HT2CMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity toward 5-HT2C receptor evaluated by displacement of [3H]-5-HT radioligand More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity toward 5-HT2C receptor evaluated by displacement of [3H]-5-HT radioligand More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]5HT from human 5HT2CMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]5HT from human 5HT2CMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Binding affinity toward 5-HT2A receptor evaluated by displacement of [125I]-DOI radioligand More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Binding affinity toward 5-HT2C receptor evaluated by displacement of [3H]-5-HT radioligand More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]-GTP-gammaS, binding (Experi...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]-5HT from human recombinant 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity toward 5-HT2B receptor evaluated by displacement of [3H]-5-HT radioligand More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of SK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Binding affinity toward 5-HT2C receptor evaluated by displacement of [3H]-5-HT radioligand More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Compound was tested in vitro for the inhibition of [3H]- 8-OH-DPAT binding to cloned cell line containing human 5-hydroxytryptamine 1A receptor (Expe...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Mus musculus (Mouse))
National Institutes of Health
Curated by ChEMBL
National Institutes of Health
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Receptor-linked G protein activation at 5-hydroxytryptamine receptor was determined by measuring the stimulation of [35S]GTP-gamma-S, bindingMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Binding affinity to human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]5HT from human 5HT2BMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair