Affinity DataKi: 280nMAssay Description:Antagonist activity at recombinant FASN thioesterase domain by fluorigenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 300nM ΔG°: -38.7kJ/molepH: 7.5 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Inhibition of fatty acid synthase KE domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 380nM ΔG°: -38.1kJ/molepH: 7.5 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Antagonist activity at human recombinant FASN thioesterase domain by fluorigenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 850nM ΔG°: -36.0kJ/molepH: 7.5 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataKi: 880nM ΔG°: -36.0kJ/molepH: 7.5 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataKi: 910nM ΔG°: -35.9kJ/molepH: 7.5 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of human FASN enoyl reductase activity using crotonyl CoA as substrate assessed as inhibition of substrate hydrolysis measured every 1 min...More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Antagonist activity at recombinant FASN thioesterase domain by fluorigenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
Affinity DataKi: 4.10E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
Affinity DataKi: 5.30E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
Affinity DataKi: 5.90E+3nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+5nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+5nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+5nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+6nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+6nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+8nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+8nMAssay Description:Inhibition constant against Escherichia coli cyclopropane fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of fatty acid synthase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.0Assay Description:Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.0Assay Description:Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of fatty acid synthase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.0Assay Description:Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of FAS by GSK2194069 was measured by an endpoint assay for thiols using a fluorescent maleimide.More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of fatty acid synthase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair