Found 1377 Enz. Inhib. hit(s) with Target = 'Low molecular weight phosphotyrosine protein phosphatase'
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Competitive inhibition of LMW-PTP (unknown origin) assessed as inhibition constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 270nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by competitive inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by competitive inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Competitive inhibition of His-tagged LMW-PTP isoform A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as ...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Competitive inhibition of LMW-PTP isoform B (unknown origin) using para-nitrophenyl phosphate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 2.23E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 2.68E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Competitive inhibition of His-tagged LMW-PTP isoform A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as ...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of LMW-PTP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectro...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 7.80E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Competitive inhibition of LMW-PTP isoform A (unknown origin)More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.48E+4nMAssay Description:Inhibition of human HCPTPAMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Mus musculus)
University Of Campinas
Curated by ChEMBL
University Of Campinas
Curated by ChEMBL
Affinity DataKi: 4.70E+4nMAssay Description:Competitive inhibition of mouse LMW-PTP expressed in Escherichia coli using pNPP substrate by Dixon plotMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 5.00E+4nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 6.00E+4nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Mus musculus)
University Of Campinas
Curated by ChEMBL
University Of Campinas
Curated by ChEMBL
Affinity DataKi: 1.24E+5nMAssay Description:Competitive inhibition of mouse LMW-PTP expressed in Escherichia coli using pNPP substrate by Dixon plotMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 1.70E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 2.40E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 6.10E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 8.80E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: 9.10E+5nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Bos taurus)
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Institute For Research In Biomedicine (Irb)
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of bovine low molecular weight PTP expressed in Escherichia coli BL21(D3) cellsMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Mus musculus)
University Of Campinas
Curated by ChEMBL
University Of Campinas
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Rattus norvegicus)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Mus musculus)
University Of Campinas
Curated by ChEMBL
University Of Campinas
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Rattus norvegicus)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 using pNPP as substrate incubated for 10 mins by microplate reader based sp...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Mus musculus)
University Of Campinas
Curated by ChEMBL
University Of Campinas
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Rattus norvegicus)
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 117nMAssay Description:Inhibition of recombinant human LMPTP-A using OMFP or pNPP as substrate by fluorescence assayMore data for this Ligand-Target Pair