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Found 16 of Enz. Inhib. data with enzyme = 'Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395]' and Substrate = 'BDBM14700'
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Rattus norvegicus (rat))
University of Copenhagen

LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  127nMpH: 8.0 T: 2°CAssay Description:To determine the inhibitory potency of the drugs, the initial velocity of the DHODR-catalyzed reaction at saturating concentrations of DHO (1 mM) and...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Rattus norvegicus (rat))
University of Copenhagen

LigandPNGBDBM16301(3-[4-(4-chlorophenyl)cyclohexyl]naphthalene-1,2,4-...)
Affinity DataIC50:  904nMpH: 8.0 T: 2°CAssay Description:To determine the inhibitory potency of the drugs, the initial velocity of the DHODR-catalyzed reaction at saturating concentrations of DHO (1 mM) and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM28815(N-(4-bromophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]p...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM28842(N-(3-fluoro-4-methylphenyl)-5-methyl-[1,2,4]triazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM28840(N-(3,4-dimethylphenyl)-5-methyl-[1,2,4]triazolo[1,...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM28810(N-(3-chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM28814(N-(4-chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM28843(N-[3-fluoro-4-(trifluoromethyl)phenyl]-5-methyl-[1...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM28817(5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM28819(5-methyl-N-[4-(trifluoromethoxy)phenyl]-[1,2,4]tri...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM28837(N-[4-chloro-3-(trifluoromethyl)phenyl]-5-methyl-[1...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM28838(N-[4-bromo-3-(trifluoromethyl)phenyl]-5-methyl-[1,...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM28839(5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM24412(5-methyl-N-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-...)
Affinity DataIC50: >2.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM24413(JMC521864 Compund DSM2 | N-(anthracen-2-yl)-5-meth...)
Affinity DataIC50: >2.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University of Washington At Seattle

LigandPNGBDBM24400(5-methyl-N-(naphthalen-2-yl)-[1,2,4]triazolo[1,5-a...)
Affinity DataIC50: >2.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed