Compile Data Set for Download or QSAR
maximum 50k data
Found 10 of Enz. Inhib. data with enzyme = 'Gag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C]' and Substrate = 'poly(rC)-oligo(dG)(12-18)'
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  85nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2481(5-Chloro-3-[(4-methylphenyl)sulfonyl]-1H-indole-2-...)
Affinity DataIC50:  110nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2482(5-Chloro-3-[(3,5-dimethylphenyl)sulfonyl]-1H-indol...)
Affinity DataIC50:  130nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2278(3-(benzenesulfonyl)-5-chloro-1H-indole-2-carboxami...)
Affinity DataIC50:  160nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2340(Pyrrolyl Aryl Sulfone (PAS) 8f | n-Propyl 1-[(2-Am...)
Affinity DataIC50:  5.00E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2338(Methyl 1-[(2-Amino-5-chlorophenyl)sulfonyl]-1H-pyr...)
Affinity DataIC50:  6.90E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2339(Pyrrolyl Aryl Sulfone (PAS) 3 | Pyrrolyl Aryl Sulf...)
Affinity DataIC50:  7.50E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2341(Isopropyl 1-[(2-Amino-5-chlorophenyl)sulfonyl]-1Hp...)
Affinity DataIC50:  8.00E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2342(Allyl 1-[(2-Amino-5-chlorophenyl)sulfonyl]-1H-pyrr...)
Affinity DataIC50:  1.40E+4nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM1434(11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...)
Affinity DataIC50: >2.00E+4nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair