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Found 18 of Enz. Inhib. data with enzyme = 'Purine nucleoside phosphorylase' and Substrate = 'BDBM22104'
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

LigandPNGBDBM22103(7-{[3,3-bis(hydroxymethyl)azetidin-1-yl]methyl}-3H...)
Affinity DataKi:  0.229nM ΔG°:  -13.0kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  0.5nM ΔG°:  -12.6kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Industrial Research

LigandPNGBDBM22103(7-{[3,3-bis(hydroxymethyl)azetidin-1-yl]methyl}-3H...)
Affinity DataKi:  0.665nM ΔG°:  -12.4kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Industrial Research

LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  1.10nM ΔG°:  -12.1kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Industrial Research

LigandPNGBDBM22108(7-{[2-(hydroxymethyl)azetidin-1-yl]methyl}-3H,4H,5...)
Affinity DataKi:  1.80nM ΔG°:  -11.8kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

LigandPNGBDBM22108(7-{[2-(hydroxymethyl)azetidin-1-yl]methyl}-3H,4H,5...)
Affinity DataKi:  1.80nM ΔG°:  -11.8kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Industrial Research

LigandPNGBDBM22105(7-{[3-(hydroxymethyl)azetidin-1-yl]methyl}-3H,4H,5...)
Affinity DataKi:  4.80nM ΔG°:  -11.2kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

LigandPNGBDBM22105(7-{[3-(hydroxymethyl)azetidin-1-yl]methyl}-3H,4H,5...)
Affinity DataKi:  6.30nM ΔG°:  -11.1kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

LigandPNGBDBM22106(7-{[(2R,4S)-2,4-bis(hydroxymethyl)azetidin-1-yl]me...)
Affinity DataKi:  12.9nM ΔG°:  -10.6kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Industrial Research

LigandPNGBDBM22106(7-{[(2R,4S)-2,4-bis(hydroxymethyl)azetidin-1-yl]me...)
Affinity DataKi:  16nM ΔG°:  -10.5kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

LigandPNGBDBM22108(7-{[2-(hydroxymethyl)azetidin-1-yl]methyl}-3H,4H,5...)
Affinity DataKi:  191nM ΔG°:  -9.07kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

LigandPNGBDBM22107(7-{[(2R,4R)-2,4-bis(hydroxymethyl)azetidin-1-yl]me...)
Affinity DataKi:  280nM ΔG°:  -8.84kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Industrial Research

LigandPNGBDBM22107(7-{[(2R,4R)-2,4-bis(hydroxymethyl)azetidin-1-yl]me...)
Affinity DataKi:  360nM ΔG°:  -8.70kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

LigandPNGBDBM22107(7-{[(2R,4R)-2,4-bis(hydroxymethyl)azetidin-1-yl]me...)
Affinity DataKi:  580nM ΔG°:  -8.42kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

LigandPNGBDBM22106(7-{[(2R,4S)-2,4-bis(hydroxymethyl)azetidin-1-yl]me...)
Affinity DataKi:  1.29E+3nM ΔG°:  -7.95kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

LigandPNGBDBM22103(7-{[3,3-bis(hydroxymethyl)azetidin-1-yl]methyl}-3H...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.75kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

LigandPNGBDBM22105(7-{[3-(hydroxymethyl)azetidin-1-yl]methyl}-3H,4H,5...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.75kcal/molepH: 7.7 T: 2°CAssay Description:PNP activity was monitored by absorbance change in a coupled assay. In the assay, inosine was converted to hypoxanthine, and then hypoxanthine was co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed