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Found 75 of Enz. Inhib. data with enzyme = 'Steroid 17-alpha-hydroxylase/17,20 lyase' and Substrate = 'to-be-curated'
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330390(US9725436, Entry 9)
Affinity DataIC50:  0.0170nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314731(US9611270, Example 21)
Affinity DataIC50:  1nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144614(US8969586, 1 | US9598436, 1)
Affinity DataIC50:  1.10nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314735(US9611270, Example 32)
Affinity DataIC50:  3nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144616(US8969586, 6 | US9598436, 6)
Affinity DataIC50:  3.20nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144623(US8969586, 86 | US9598436, 86)
Affinity DataIC50:  3.90nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144626(US8969586, 99 | US9598436, 99)
Affinity DataIC50:  4nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144627(US8969586, 103 | US9598436, 103)
Affinity DataIC50:  4nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM50358201(CHEMBL1921976 | US9611270, orteronel)
Affinity DataIC50:  4nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330391(US9725436, Entry 10)
Affinity DataIC50:  5nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330383(US9725436, Entry 3)
Affinity DataIC50:  5nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314733(US9611270, Example 30)
Affinity DataIC50:  5nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330384(US9725436, Entry 4)
Affinity DataIC50:  5nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330386(US9725436, Entry 6)
Affinity DataIC50:  5nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330388(US9725436, Entry 7)
Affinity DataIC50:  5nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330389(US9725436, Entry 8)
Affinity DataIC50:  5nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144625(US8969586, 98 | US9598436, 98)
Affinity DataIC50:  8nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330385(US9725436, Entry 5)
Affinity DataIC50:  18nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330393(US9725436, Entry 12)
Affinity DataIC50:  39nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330396(US9725436, Entry 15)
Affinity DataIC50:  42nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144620(US8969586, 52 | US9598436, 52)
Affinity DataIC50:  42nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144619(US8969586, 30 | US9598436, 30)
Affinity DataIC50:  48nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144628(US8969586, 109 | US9598436, 109)
Affinity DataIC50:  56nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330392(US9725436, Entry 11)
Affinity DataIC50:  58nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144618(US8969586, 26 | US9598436, 26)
Affinity DataIC50:  65nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144624(US8969586, 94 | US9598436, 94)
Affinity DataIC50:  76nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144631(US8969586, 129 | US9598436, 129)
Affinity DataIC50:  79nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330397(US9725436, Entry 16)
Affinity DataIC50:  86nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330398(US9725436, Entry 17)
Affinity DataIC50:  100nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330395(US9725436, Entry 14)
Affinity DataIC50:  117nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314740(US9611270, Example 42)
Affinity DataIC50:  120nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)
Affinity DataIC50:  130nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314736(US9611270, Example 33)
Affinity DataIC50:  150nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314738(US9611270, Example 38)
Affinity DataIC50:  174nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330382(US9725436, Entry 2)
Affinity DataIC50:  180nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314739(US9611270, Example 39 | US9611270, Example 41)
Affinity DataIC50:  183nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144617(US8969586, 14 | US9598436, 14)
Affinity DataIC50:  192nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314734(US9611270, Example 31)
Affinity DataIC50:  199nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314732(US9611270, Example 29)
Affinity DataIC50:  208nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314737(US9611270, Example 37)
Affinity DataIC50:  244nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144630(US8969586, 128 | US9598436, 128)
Affinity DataIC50:  251nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM50435990(GALETERONE | TOK-001 | US9611270, galaterone | VN/...)
Affinity DataIC50:  282nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144615(US8969586, 4 | US9598436, 4)
Affinity DataIC50:  357nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330388(US9725436, Entry 7)
Affinity DataIC50:  416nMAssay Description:Cyp21 assay protocol: AD293 cells that stably over-express recombinant CYP-21 were seeded in 96 well plates coated with poly D-lysine (10,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314730(US9611270, Example 8)
Affinity DataIC50:  428nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM302871(3-(2-Methoxyethoxy)-7-(4-methylpyridin-3-yl)benzo[...)
Affinity DataIC50:  524nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144621(US8969586, 57 | US9598436, 57)
Affinity DataIC50:  524nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330389(US9725436, Entry 8)
Affinity DataIC50:  565nMAssay Description:Cyp21 assay protocol: AD293 cells that stably over-express recombinant CYP-21 were seeded in 96 well plates coated with poly D-lysine (10,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM144629(US8969586, 124 | US9598436, 124)
Affinity DataIC50:  611nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330393(US9725436, Entry 12)
Affinity DataIC50:  700nMAssay Description:Cyp21 assay protocol: AD293 cells that stably over-express recombinant CYP-21 were seeded in 96 well plates coated with poly D-lysine (10,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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