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Found 31 of Enz. Inhib. data with enzyme = 'Tyrosine-protein kinase FRK' and Substrate = 'to-be-curated'
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataKi:  4.72E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184777(CHEMBL3823104 | US10294227, Code 519)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM387846(US10294227, Code 503)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM387836(US10294227, Code 585 | tert-butyl N-[4-[4-amino-1-...)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184777(CHEMBL3823104 | US10294227, Code 519)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184776(CHEMBL3824233 | US10294227, Code 518)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184767(CHEMBL3824089 | US10294227, Code 506)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184776(CHEMBL3824233 | US10294227, Code 518)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184767(CHEMBL3824089 | US10294227, Code 506)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184786(CHEMBL3824116 | US10294227, Code 565)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM378885(US10266537, Compound 93)
Affinity DataIC50:  19nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184785(CHEMBL3823620 | US10294227, Code 553)
Affinity DataIC50:  55nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184785(CHEMBL3823620 | US10294227, Code 553)
Affinity DataIC50:  55nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184769(CHEMBL3823212 | US10294227, Code 109)
Affinity DataIC50:  550nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184766(CHEMBL3823861 | US10294227, Code 221)
Affinity DataIC50:  550nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM387845(US10294227, Code 402)
Affinity DataIC50:  550nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184781(CHEMBL3823543 | US10294227, Code 533)
Affinity DataIC50:  550nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM387854(US10294227, Code 584)
Affinity DataIC50:  550nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184782(CHEMBL3824228 | US10294227, Code 543)
Affinity DataIC50:  550nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184781(CHEMBL3823543 | US10294227, Code 533)
Affinity DataIC50:  550nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM387840(US10294227, Code 105)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184784(CHEMBL3824021 | US10294227, Code 556)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184772(CHEMBL3822591 | US10294227, Code 113)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184778(CHEMBL3823711 | US10294227, Code 540)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184770(CHEMBL3823849 | US10294227, Code 112)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50184780(CHEMBL3823255 | US10294227, Code 526)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM387839(US10294227, Code 103)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent