Affinity DataKi: 0.310nM Kon: 0.00000207M-1s-1 Koff: 6.63E+3s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nM Kon: 0.00000617M-1s-1 Koff: 6.46E+4s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nM Kon: 0.00000871M-1s-1 Koff: 1.32E+3s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.73nM Kon: 0.0000109M-1s-1 Koff: 6.31E+3s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.58nM Kon: 0.0000112M-1s-1 Koff: 7.08E+3s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nM Kon: 0.0000117M-1s-1 Koff: 1.02E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKon: 0.0000120M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKon: 0.0000120M-1s-1 Koff: 4.45E+4s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 100nM Kon: 0.0000138M-1s-1 Koff: 132s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 5.01nM Kon: 0.0000141M-1s-1 Koff: 2.88E+3s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0430nM Kon: 0.0000145M-1s-1 Koff: 3.39E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nM Kon: 0.0000151M-1s-1 Koff: 2.57E+3s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKon: 0.0000160M-1s-1 Koff: 1.10E+3s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 1.58nM Kon: 0.0000178M-1s-1 Koff: 1.18E+4s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 79.4nM Kon: 0.0000178M-1s-1 Koff: 229s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKon: 0.0000180M-1s-1Assay Description:Rate of deacylation by human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nM Kon: 0.0000182M-1s-1 Koff: 4.57E+4s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 251nM Kon: 0.0000182M-1s-1 Koff: 75.9s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nM Kon: 0.0000200M-1s-1 Koff: 15.8s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 398nM Kon: 0.0000240M-1s-1 Koff: 66.1s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKon: 0.0000240M-1s-1 Koff: 2.15E+4s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKon: 0.0000240M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKon: 0.0000270M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKon: 0.0000270M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKon: 0.0000280M-1s-1 Koff: 9.40E+4s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKon: 0.0000280M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 15.8nM Kon: 0.0000282M-1s-1 Koff: 1.66E+3s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKon: 0.0000290M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKon: 0.0000290M-1s-1 Koff: 4.90E+4s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 17.9nM Kon: 0.0000292M-1s-1 Koff: 1.63E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 133nM Kon: 0.0000292M-1s-1 Koff: 219s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKon: 0.0000300M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 100nM Kon: 0.0000372M-1s-1 Koff: 363s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 398nM Kon: 0.0000389M-1s-1 Koff: 97.7s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nM Kon: 0.0000436M-1s-1 Koff: 7.59E+3s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKon: 0.0000470M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 51nM Kon: 0.0000515M-1s-1 Koff: 1.01E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 0.0710nM Kon: 0.0000550M-1s-1 Koff: 7.76E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKon: 0.0000560M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKon: 0.0000560M-1s-1 Koff: 9.40E+4s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 12.6nM Kon: 0.0000562M-1s-1 Koff: 4.68E+3s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKon: 0.0000610M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 16.3nM Kon: 0.0000612M-1s-1 Koff: 3.75E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 4.02nM Kon: 0.0000628M-1s-1 Koff: 1.56E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKon: 0.0000660M-1s-1Assay Description:Rate of deacylation by human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nM Kon: 0.0000661M-1s-1 Koff: 3.47E+5s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1nM Kon: 0.0000661M-1s-1 Koff: 7.08E+4s-1Assay Description:Component deacylation rate constant for interaction with human leukocyte elastaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 290nM Kon: 0.0000692M-1s-1 Koff: 239s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKon: 0.0000700M-1s-1 Koff: 1.00E+4s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKon: 0.0000700M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair