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Found 21 Enz. Inhib. hit(s) with all data for entry = 50013602
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132386((6,7-Dimethoxy-quinoxalin-2-yl)-phenyl-amine | CHE...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132406(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-2-methyl-cy...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132405(5-(6,7-Dimethoxy-quinoxalin-2-ylamino)-bicyclo[2.2...)
Affinity DataIC50:  24nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132409(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Affinity DataIC50:  28nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132395((6,7-Dimethoxy-quinoxalin-2-yl)-(3-methyl-cyclohex...)
Affinity DataIC50:  41nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132409(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Affinity DataIC50:  49nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132407(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexano...)
Affinity DataIC50:  68nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(4-((R)-6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohe...)
Affinity DataIC50:  76nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132399(CHEMBL107402 | Cyclohexyl-(6,7-dimethoxy-quinoxali...)
Affinity DataIC50:  124nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(4-((R)-6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohe...)
Affinity DataIC50:  299nMAssay Description:Inhibition of Mitogenesis, PDGF-AA, assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132409(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Affinity DataIC50:  345nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(4-((R)-6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohe...)
Affinity DataIC50:  353nMAssay Description:Inhibition of Mitogenesis, PDGF-BB, assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50039082(6,7-Dimethoxy-3-thiophen-3-yl-quinoline | CHEMBL66...)
Affinity DataIC50:  461nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132404(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Affinity DataIC50:  930nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(4-((R)-6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohe...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132408(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(4-((R)-6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohe...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(4-((R)-6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohe...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of Insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(4-((R)-6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohe...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Janus kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(4-((R)-6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohe...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Janus kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10/8/9(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132391(4-((R)-6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohe...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed