Compile Data Set for Download or QSAR
maximum 50k data
Found 74 Enz. Inhib. hit(s) with all data for entry = 8891
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426578(N,N′-(13,20 dioxo-3, 6, 9, 24, 27, 30-hexaox...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426619((S or R)—N,N′-(13,20-dioxo-3,6,9,24,27,...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426580(N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426581(N1,N4-bis(2-(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426582(N1,N31-bis(2-(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426583(N,N′-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-di...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426522(N-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-3-(...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426587(N1,N4-bis(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426588(N1,N4-bis(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426589(2,2′-oxybis(N-(2-(2-(2-(3-(6,8-dichloro-2-me...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426590(N1,N4-bis(2-(2-(2-(4-((S or R)-6,8-dichloro-2-meth...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426591(2,2′-oxybis(N-(2-(2-(2-(4-((S or R)-6,8-dich...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426602((S or R)—N,N′-(10,17-dioxo-3,6,21,24-te...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426603((S or R)—N,N′-(2,2′-(2,2′-(...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426604(N,N′-(butane-1,4-diyl)bis(2-(2-(2-(4-(6,8-di...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426605(N1,N4-bis(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426606(N,N′-(2,2′-(2,2′-(2,2′-(1,...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426607(N,N′-(13,20-dioxo-3,6,9,24,27,30-hexaoxa-12,...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426608((2R,3R)—N1,N4-bis(2-(2-(2-(2-(4-(4-((E)-3-(di...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426609(N1,N3,N5-tris(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426610(N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426611((2S,3S)—N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426612(N1,N4-bis(2-(2-(2-(2-(3-((S or R)-6,8-dichloro-2-m...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426613((2R,3S)—N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426614(N1,N2-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426615(N,N′-(10,17-dioxo-3,6,21,24-tetraoxa-9,11,16...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426616(N,N′-(2,2′-(2,2′-(2,2′-(1,...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426617((S or R)—N,N′-(13,20-dioxo-3,6,9,24,27,...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426618((S or R)—N,N′-(13-oxo-3,6,9,17,20,23-he...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426579(N,N′-(2,2′-(2,2′-(2,2′-(2,...)
Affinity DataIC50: <100nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426522(N-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-3-(...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426523(N1,N8-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM381646(US10272079, Compound 4 | US10543207, Example 45)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426525(N,N′-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-di...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426526(4-(3-(6-chloro-2-(diaminomethyleneamino)quinazolin...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426527(1-(4-(3-(4-(3-aminopropyl)piperazin-1-yl)phenyl)-6...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426528(4-(4-(6-chloro-2-(diaminomethyleneamino)quinazolin...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426529(2-(4-(3-(4-(3-guanidinopropyl)piperazin-1-yl)pheny...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426530(2-(6-chloro-4-(3-(4-(2-hydroxyethyl)piperazin-1-yl...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426531(2-(6-chloro-4-(4-(4-(2-hydroxyethyl)piperazin-1-yl...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426532(N1,N31-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426533(N,N′-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-di...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426534(N1,N31-bis(2-(2-(2-(2-(4-(4-((E)-3-(diaminomethyle...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426535(N1,N4-bis(20-(4-(4-((E)-3-(diaminomethyleneamino)-...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426536(N1,N4-bis(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetr...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426537(N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-ethyl-1,2,...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426538(2,2′-oxybis(N-(2-(2-(2-(4-(6,8-dichloro-2-me...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426539((2R,3R)—N1,N4-bis(2-(2-(2-(4-(6,8-dichloro-2-...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426540((2R,3R)—N1,N4-bis(20-(4-(4-((E)-3-(diaminomet...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM426541((E)-3-(4-(4-(N-(20-amino-3,6,9,12,15,18-hexaoxaico...)
Affinity DataIC50:  316nMAssay Description:Rat NHE-3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensitive dye method originally reported by Tsien (Proc. Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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