Compile Data Set for Download or QSAR
maximum 50k data
Found 59 Enz. Inhib. hit(s) with all data for entry = 11586
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629221(Synthesis of 4-(1-(4-fluorophenyl)-5-hydroxy-2-(1-...)
Affinity DataIC50: <2.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629222(Synthesis of 4-(2-(I-cyano-2-methylpropan-2-yl)-1-...)
Affinity DataIC50: <2.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629189(US20230339915, Compound 57)
Affinity DataIC50: <2.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629223(US20230339915, Compound 167)
Affinity DataIC50: <2.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629225(US20230339915, Compound 170)
Affinity DataIC50: <2.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629227(Synthesis of 4-(6-chloro-1-(4-fluorophenyl)-5-hydr...)
Affinity DataIC50: <2.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629228(Synthesis of 4-(4-chloro-1-(4-fluorophenyl)-5-hydr...)
Affinity DataIC50: <2.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629202(US20230339915, Compound 80)
Affinity DataIC50: <2.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629218(US20230339915, Compound 148)
Affinity DataIC50: <2.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629207(US20230339915, Compound 97)
Affinity DataIC50:  3.50E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629224(US20230339915, Compound 168)
Affinity DataIC50:  3.50E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629203(US20230339915, Compound 89)
Affinity DataIC50:  3.50E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629190(US20230339915, Compound 58)
Affinity DataIC50:  3.50E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629183(US20230339915, Compound 22)
Affinity DataIC50:  3.50E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629226(US20230339915, Compound 172)
Affinity DataIC50:  3.50E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629219(US20230339915, Compound 149)
Affinity DataIC50:  3.50E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629199(US20230339915, Compound 77)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629200(US20230339915, Compound 78)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629201(US20230339915, Compound 79)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629204(US20230339915, Compound 90)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629205(US20230339915, Compound 92)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629206(US20230339915, Compound 95)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629208(US20230339915, Compound 99)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629209(US20230339915, Compound 104)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629210(US20230339915, Compound 108)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629211(US20230339915, Compound 129)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629212(US20230339915, Compound 130)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629213(US20230339915, Compound 134)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629214(Synthesis of trans-3-(1-(4-fluoro-3-methylphenyl)-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629215(6-(1-(4-fluoro-3-methylphenyl)-5-hydroxy-2-(triflu...)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629216(US20230339915, Compound 141)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629217(US20230339915, Compound 145)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629220(6-(1-(4-fluoro-3-methylphenyl)-5-hydroxy-2-(triflu...)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629229(US20230339915, Compound 181)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629230(1-(1-(4-fluorophenyl)-5-hydroxy-2-methyl-1H-indol-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629231(US20230339915, Compound 186)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629232(US20230339915, Compound 190)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629233(3-(1-(4-fluoro-3-methylphenyl)-5-hydroxy-2-isoprop...)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629234(3-[1-(4-fluoro-3-methyl-phenyl)-5-hydroxy-2-isopro...)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629235(N-((3-(1-(4-fluoro-3-methylphenyl)-5-hydroxy-2-iso...)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629236(1-(4-fluoro-3-methyl-phenyl)-2-isopropyl-3-[3-(2H-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629237(US20230339915, Compound 219)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629198(US20230339915, Compound 75)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629197(US20230339915, Compound 71)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629196(US20230339915, Compound 69)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629195(US20230339915, Compound 68)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629194(US20230339915, Compound 63)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629193(US20230339915, Compound 61)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629192(US20230339915, Compound 60)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1-antitrypsin(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM629191(US20230339915, Compound 59)
Affinity DataIC50: >5.00E+3nMAssay Description:Assay Protocol: Pre-Incubation of Z-AAT with Compounds1. 7.5 μL of Z-AAT (20 nM) was incubated with compounds 1-227 in a GCA plate for 1 hour at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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