Compile Data Set for Download or QSAR
maximum 50k data
Found 189 Enz. Inhib. hit(s) with all data for entry = 11590
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629709((3R)-16-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-...)
Affinity DataIC50:  7nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629708((4R,Z)-2,2-difluoro-66-(1-isopropylpiperidin-4-yl)...)
Affinity DataIC50:  8nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM50581659(CHEMBL4519023 | US20230339952, Comparative Compoun...)
Affinity DataIC50:  11nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629621((3R)-42,5,5-trifluoro-16-(4-isopropylpiperazin-1-y...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629622((R)-1-(2,2-difluoro-4-methyl-7-oxa-5-aza-6(4,7)- p...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629623(15-fluoro-57-methoxy-52,3-dimethyl-6,9,12,15,18- p...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629624((3R)-42,5,5-trifluoro-16-(1-isopropylpiperidin-4-y...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629625((R)-2,2-difluoro-64,4-dimethyl-67-morpholino-7-oxa...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629626((4R,Z)-66-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629627((4R)-66-(1,1-dioxidotetrahydro-2H-thiopyran-4-y])-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629628(1-((4R)-2,2-difluoro-4-methyl-67,11-dioxo-67,68- d...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629629((11S,15R,4R)-66-(1,1-dioxidotetrahydro-2H- thiopyr...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629630((14S,4R)-66-(1,1-dioxidotetrahydro-2H-thiopyran-4-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629631(1-((4R)-32,2,2-trifluoro-4-methyl-67,12-dioxo-67,6...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629632((4R,E)-2,2-difluoro-66-(1-isopropylpiperidin-4-yl)...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629633((3R)-16-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629634((4R,12R)-66-(1,1-dioxidotetrahydro-2H-thiopyran-4-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629635(1-((4R,13S)-2,2-difluoro-4,13-dimethyl-67,12-dioxo...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629636((3R)-5,5-difluoro-16-(4-isopropylpiperazin-1-yl)-3...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629637((4R)-66-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629638((3R)-16-(1,1-dioxidothiomorpholino)-42,5,5-trifluo...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629639((3R)-16-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629640(1-((4R)-32,2,2-trifluoro-4-methyl-67,8-dioxo-67,68...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629641(1-((4R,Z)-2,2-difluoro-4-methyl-67-oxo-67,68- dihy...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629642((6R,Z)-86-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629643((3R)-16-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629644((4R)-32,2,2-trifluoro-66-(1-isopropylpiperidin-4-y...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629645((4R)-2,2-difluoro-66-(4-isopropylpiperazin-1-yl)-4...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629646((4R)-66-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629647((4R)-66-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629648(1-((4R,Z)-2,2-difluoro-62,4-dimethyl-67-oxo-67,68-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629649(1-((4R)-32,2,2-trifluoro-62,4-dimethyl-67-oxo-67,6...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629650(1-((4R,Z)-32,2,2-trifluoro-62,4-dimethyl-67-oxo-67...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629651(1-((4R)-2,2-difluoro-62,4-dimethyl-67-oxo-67,68- d...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629652(1-((4R,Z)-32,2,2-trifluoro-62,4-dimethyl-67-oxo-67...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629653(1-((4R,Z)-2,2-difluoro-62,4-dimethyl-67-oxo-67,68-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629654((4R)-66-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629655((4R,Z)-66-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629656((R)-4-(32,2,2-trifluoro-68-methoxy-4-methyl-7-oxa-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629657((4R)-32,2,2-trifluoro-4-methyl-66-(4-(1- methylpip...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629658((4R)-32,2,2-trifluoro-4-methyl-66-(4-(oxetan-3- yl...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629659((4R)-32,2,2-trifluoro-4-methyl-66-(4- (methylsulfo...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629660((3R)-16-(1,1-dioxidothiomorpholino)-5,5-difluoro-3...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629661((3R)-5,5-difluoro-16-(1-isopropylpiperidin-4-yl)-3...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629662((4R)-66-(1,1-dioxidothiomorpholino)-2,2-difluoro-4...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629663((4R,12R)-66-(1,1-dioxidotetrahydro-2H-thiopyran-4-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629664((4R,12S)-66-(1,1-dioxidotetrahydro-2H-thiopyran-4-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629665(4-((3R)-5,5-difluoro-3-methyl-17-oxo-17,18-dihydro...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629666((4R)-2,2-difluoro-66-(4-isopropylpiperazin-1-yl)-4...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Homo sapiens (Human))
Kumquat Biosciences

US Patent
LigandPNGBDBM629667((3R)-16-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-...)
Affinity DataIC50: <100nMAssay Description:The assay buffer can contain 5 mM HEPES pH 7.4, 150 mM NaCl, 10 mM EDTA, 1 mM DTT, 0.05% BSA, 0.0025% (v/v) Igepal and 100 mM KF. A Ras working solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 189 total ) | Next | Last >>
Jump to: