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Found 6 Enz. Inhib. hit(s) with all data for entry = 6392
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126005(US8772282, 1 | US8772282, 203)
Affinity DataIC50:  64.4nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126007(US8772282, 16)
Affinity DataIC50:  77.3nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126012(US8772282, 32)
Affinity DataIC50:  91.2nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126011(US8772282, 31)
Affinity DataIC50:  110nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126010(US8772282, 30)
Affinity DataIC50:  166nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM126009(US8772282, 23)
Affinity DataIC50:  172nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent